DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab10 and RAB13

DIOPT Version :9

Sequence 1:	NP_523419.1	Gene:	Rab10 / 33025	FlyBaseID:	FBgn0015789	Length:	204	Species:	Drosophila melanogaster
Sequence 2:	NP_002861.1	Gene:	RAB13 / 5872	HGNCID:	9762	Length:	203	Species:	Homo sapiens

Alignment Length:	199	Identity:	124/199 - (62%)
Similarity:	157/199 - (78%)	Gaps:	1/199 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 KTYDLLFKLLLIGDSGVGKTCILFRFSDDAFTSTFISTIGIDFKIKTVELRGKKIKLQIWDTAGQ 68
            |.||.||||||||||||||||::.||::|.|.:|:||||||||||:||::.|||||||:||||||
Human     3 KAYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKIKLQVWDTAGQ 67

  Fly    69 ERFHTITTSYYRGAMGIMLVYDITNEKSFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVN 133
            |||.||||:||||||||:||||||:|||||||..|:::|.|:|:..||:::|||||||..||.|.
Human    68 ERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLGNKCDMEAKRKVQ 132

  Fly   134 KERGEAIAREHGIRFMETSAKSNINIERAFCELAEAILDKTSGRESAENQERVIIDRRNQEKAPG 198
            ||:.:.:||||||||.||||||::|::.||..||..||.|:.||.|....:....|.:..:| ..
Human   133 KEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDILLKSGGRRSGNGNKPPSTDLKTCDK-KN 196

  Fly   199 YSKC 202
            .:||
Human   197 TNKC 200

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab10	NP_523419.1	Rab8_Rab10_Rab13_like	7..173	CDD:206659	114/165 (69%)
RAB13	NP_002861.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	114/165 (69%)
		Effector region. /evidence=ECO:0000250	37..45		6/7 (86%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	173..203		7/29 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0078
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1426655at2759
OrthoFinder	1	1.000	-	-		FOG0000502
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1998
SonicParanoid	1	1.000	-	-		X312
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.850