DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab10 and RAB3B

DIOPT Version :9

Sequence 1:	NP_523419.1	Gene:	Rab10 / 33025	FlyBaseID:	FBgn0015789	Length:	204	Species:	Drosophila melanogaster
Sequence 2:	NP_002858.2	Gene:	RAB3B / 5865	HGNCID:	9778	Length:	219	Species:	Homo sapiens

Alignment Length:	189	Identity:	95/189 - (50%)
Similarity:	136/189 - (71%)	Gaps:	2/189 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 KTYDLLFKLLLIGDSGVGKTCILFRFSDDAFTSTFISTIGIDFKIKTVELRGKKIKLQIWDTAGQ 68
            :.:|.:||||:||:|.||||..|||::||.||..|:||:|||||:|||....|::||||||||||
Human    17 QNFDYMFKLLIIGNSSVGKTSFLFRYADDTFTPAFVSTVGIDFKVKTVYRHEKRVKLQIWDTAGQ 81

  Fly    69 ERFHTITTSYYRGAMGIMLVYDITNEKSFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVN 133
            ||:.||||:|||||||.:|:||||||:||..:..|...|..::.::.:.:::||||||.::|||.
Human    82 ERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWATQIKTYSWDNAQVILVGNKCDMEEERVVP 146

  Fly   134 KERGEAIAREHGIRFMETSAKSNINIERAFCELAEAILDKTSGRESAENQERVIIDRRN 192
            .|:|:.:|.:.|..|.|.|||.||::.:||..|.:||.||.|  :|.:....::...:|
Human   147 TEKGQLLAEQLGFDFFEASAKENISVRQAFERLVDAICDKMS--DSLDTDPSMLGSSKN 203

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab10	NP_523419.1	Rab8_Rab10_Rab13_like	7..173	CDD:206659	90/165 (55%)
RAB3B	NP_002858.2	Rab3	22..186	CDD:206657	89/163 (55%)
		RAB	23..183	CDD:197555	87/159 (55%)
		Effector region. /evidence=ECO:0000250	51..59		5/7 (71%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1426655at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920