Protein Alignment Rab10 and RAB1A

DIOPT Version :10

• Sequence 1: NP_523419.1
• Gene: Rab10 / 33025
• FlyBaseID: FBgn0015789
• Length: 204
• Species: Drosophila melanogaster
• Sequence 2: NP_004152.1
• Gene: RAB1A / 5861
• HGNCID: 9758
• Length: 205
• Species: Homo sapiens
• Alignment Length: 198
• Identity: 104/198 - (52%)
• Similarity: 145/198 - (73%)
• Gaps: 0/198 - (0%)

  Fly     6 YDLLFKLLLIGDSGVGKTCILFRFSDDAFTSTFISTIGIDFKIKTVELRGKKIKLQIWDTAGQER 70
            ||.||||||||||||||:|:|.||:||.:|.::|||||:||||:|:||.||.|||||||||||||
Human     8 YDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQER 72

  Fly    71 FHTITTSYYRGAMGIMLVYDITNEKSFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVNKE 135
            |.|||:||||||.||::|||:|:::||.|:.:||:.||.:|:|:|.|:::|||||:|.|:||:..
Human    73 FRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYT 137

  Fly   136 RGEAIAREHGIRFMETSAKSNINIERAFCELAEAILDKTSGRESAENQERVIIDRRNQEKAPGYS 200
            ..:..|...||.|:|||||:..|:|::|..:|..|..:.....:|...|:..:..::........
Human   138 TAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTPVKQSGG 202

  Fly   201 KCC 203
            .||
Human   203 GCC 205

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab10	NP_523419.1	Rab8_Rab10_Rab13_like	7..173	CDD:206659	99/165 (60%)
RAB1A	NP_004152.1	Rab1_Ypt1	10..175	CDD:206661	98/164 (60%)
		Switch 1. /evidence=ECO:0000269|PubMed:22416225, ECO:0007744|PDB:3SFV, ECO:0007744|PDB:3TKL	34..48		7/13 (54%)
		Switch 2. /evidence=ECO:0000269|PubMed:22416225, ECO:0007744|PDB:3SFV, ECO:0007744|PDB:3TKL	66..83		14/16 (88%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	178..205		2/26 (8%)