DRSC/TRiP Functional Genomics Resources

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Protein Alignment Rab10 and RAB40C

DIOPT Version :9

Sequence 1:NP_523419.1 Gene:Rab10 / 33025 FlyBaseID:FBgn0015789 Length:204 Species:Drosophila melanogaster
Sequence 2:NP_001166134.1 Gene:RAB40C / 57799 HGNCID:18285 Length:281 Species:Homo sapiens


Alignment Length:183 Identity:81/183 - (44%)
Similarity:113/183 - (61%) Gaps:2/183 - (1%)


- Green bases have known domain annotations that are detailed below.


  Fly     4 KTYDLLFKLLLIGDSGVGKTCILFRFSDDAFTSTFISTIGIDFKIKTVELRGKKIKLQIWDTAGQ 68
            |:||.|.|.||:|||.|||..||....|.|..|.:..:.|||:|..|:.|.|:::||::|||:||
Human     9 KSYDYLLKFLLVGDSDVGKGEILESLQDGAAESPYAYSNGIDYKTTTILLDGRRVKLELWDTSGQ 73

  Fly    69 ERFHTITTSYYRGAMGIMLVYDITNEKSFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVN 133
            .||.||..||.|||.||:|||||||..||:.|.:|::.||||| ..|.::::||:..:..||.|.
Human    74 GRFCTIFRSYSRGAQGILLVYDITNRWSFDGIDRWIKEIDEHA-PGVPRILVGNRLHLAFKRQVP 137

  Fly   134 KERGEAIAREHGIRFMETSAKSNINIERAFCELAEAILDKTSGRESAENQERV 186
            .|:..|.|.::.:.|.|.|...|.|:..:|.||:..:|.: .|.|......||
Human   138 TEQARAYAEKNCMTFFEVSPLCNFNVIESFTELSRIVLMR-HGMEKIWRPNRV 189

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rab10NP_523419.1 Rab8_Rab10_Rab13_like 7..173 CDD:206659 75/165 (45%)
RAB40CNP_001166134.1 Rab40 9..281 CDD:133321 81/183 (44%)
SOCS_Rab40 187..229 CDD:239711 2/3 (67%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 245..281
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0078
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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