DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab10 and zgc:162879

DIOPT Version :9

Sequence 1:	NP_523419.1	Gene:	Rab10 / 33025	FlyBaseID:	FBgn0015789	Length:	204	Species:	Drosophila melanogaster
Sequence 2:	NP_001082896.1	Gene:	zgc:162879 / 572256	ZFINID:	ZDB-GENE-070424-92	Length:	663	Species:	Danio rerio

Alignment Length:	206	Identity:	80/206 - (38%)
Similarity:	120/206 - (58%)	Gaps:	12/206 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 TYDL--LFKLLLIGDSGVGKTCILFRFSDDAFTSTFISTIGIDFKIKTVELRGKKIKLQIWDTAG 67
            |.||  :::|:|.||:|.||:..|.|.|.:.|.....:|:|:||:||.:.:.|:|..||||||||
Zfish   461 TQDLAPVYRLVLAGDAGSGKSSFLLRLSLNEFRGDIQTTLGVDFQIKKMLVDGEKTNLQIWDTAG 525

  Fly    68 QERFHTITTSYYRGAMGIMLVYDITNEKSFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKR-- 130
            ||||.:|..||:|.|.|::|:||:|:|.||.|:.:|:..|.|..:||:...|:|||.|:...|
Zfish   526 QERFRSIARSYFRKAHGVLLLYDVTSESSFLNVREWVEQIRESTDEDIPMCIIGNKVDLRAARPE 590

  Fly   131 --VVNKERGEAIAREHGIRFMETSAKSNINIERAFCELAEAILDKTS-GRESAENQERVIIDRRN 192
              .|:...||.:|..:...|.|.|||...::..|...||..:..... ||.| |:|.::.:.:|.
Zfish   591 GSCVSSIHGEKLAMNYNALFCEASAKEGTSVIEAVLHLAREVKKHVKLGRRS-ESQVKLSLHKRR 654

  Fly   193 QEKAPGYSKCC 203
            :.    .|.||
Zfish   655 KT----LSNCC 661

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab10	NP_523419.1	Rab8_Rab10_Rab13_like	7..173	CDD:206659	70/171 (41%)
zgc:162879	NP_001082896.1	EFh	5..60	CDD:238008
		EF-hand_7	6..60	CDD:290234
		TMPIT	104..>187	CDD:285135
		RILP-like	<180..290	CDD:304877
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	324..343
		RAB	468..634	CDD:197555	68/165 (41%)
		Rab	468..630	CDD:206640	67/161 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0078
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900