DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rab10 and rasef

DIOPT Version :9

Sequence 1:	NP_523419.1	Gene:	Rab10 / 33025	FlyBaseID:	FBgn0015789	Length:	204	Species:	Drosophila melanogaster
Sequence 2:	XP_699335.4	Gene:	rasef / 570731	ZFINID:	ZDB-GENE-081105-157	Length:	706	Species:	Danio rerio

Alignment Length:	202	Identity:	70/202 - (34%)
Similarity:	114/202 - (56%)	Gaps:	13/202 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 FKLLLIGDSGVGKTCILFRFSDDAFTSTFISTIGIDFKIKTVELRGKKIKLQIWDTAGQERFHTI 74
            ::::|.||:.|||:..|.|...:.|.....:|:|:||::||:.:.|....||:|||||||||.:|
Zfish   508 YRIVLAGDAAVGKSSFLLRLCKNEFKGNTSATLGVDFQMKTLVVDGVPTVLQLWDTAGQERFRSI 572

  Fly    75 TTSYYRGAMGIMLVYDITNEKSFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRV------VN 133
            ..||:|.|.|::|:||:|.||||.|:.:|:..|::.:.:|:..|::|||.|:..:.:      :.
Zfish   573 AKSYFRRADGVLLLYDVTCEKSFLNVREWVDIIEDVSQDDIPIMLVGNKTDLRKEALQDGVTCIP 637

  Fly   134 KERGEAIAREHGIRFMETSAKSNINIERAFCELAEAILDKTSGRESAENQERVIIDR--RNQEKA 196
            ...||.:|..:...|.|||||...||..|...||..:.     :.:.:.:|.|.:.:  .|..|.
Zfish   638 TSYGEKLAMTYSALFCETSAKDGSNIIEAVLHLAREVT-----KHADDYKEPVSVAKLSGNHTKK 697

  Fly   197 PGYSKCC 203
            .....||
Zfish   698 MSSPNCC 704

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab10	NP_523419.1	Rab8_Rab10_Rab13_like	7..173	CDD:206659	64/168 (38%)
rasef	XP_699335.4	EFh	9..69	CDD:238008
		EF-hand_7	10..68	CDD:290234
		DUF904	201..>253	CDD:283624
		RAB	508..674	CDD:197555	64/165 (39%)
		Rab	508..672	CDD:206640	63/163 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0078
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.900