DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab10 and rab44

DIOPT Version :9

Sequence 1:	NP_523419.1	Gene:	Rab10 / 33025	FlyBaseID:	FBgn0015789	Length:	204	Species:	Drosophila melanogaster
Sequence 2:	XP_689291.6	Gene:	rab44 / 560799	ZFINID:	ZDB-GENE-040724-117	Length:	2402	Species:	Danio rerio

Alignment Length:	194	Identity:	83/194 - (42%)
Similarity:	119/194 - (61%)	Gaps:	9/194 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 FKLLLIGDSGVGKTCILFRFSDDAFTSTFISTIGIDFKIKTVELRGKKIKLQIWDTAGQERFHTI 74
            |.::::|:|.||||..:.||.:..||..:.||||:|..::||||..:.:||||||||||||||:|
Zfish  2218 FNVVMVGNSCVGKTSFIRRFHEGQFTEDYRSTIGVDTFVQTVELPDRTVKLQIWDTAGQERFHSI 2282

  Fly    75 TTSYYRGAMGIMLVYDITNEKSFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVNKERGEA 139
            ||..:..|.|::|:|:||..|||.:|..|:....|.|.:||..|:||||.|..::.|..:| |..
Zfish  2283 TTQVFHKAEGLLLMYEITCSKSFISIRDWISQARERAQDDVVMMLLGNKNDSVNREVQIQE-GAD 2346

  Fly   140 IAREHGIRFMETSAKSNINIERAFCELAEAILDKTSGRESAENQERVIIDRRNQEKAPGYSKCC 203
            :|||:.|.|||.||.:..|:..:...|||.::.:...||     |...:.|..|:|..|   ||
Zfish  2347 LAREYNIHFMECSAANGANVSESMRTLAELLVQRKRKRE-----EHTTLRREPQQKKSG---CC 2402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab10	NP_523419.1	Rab8_Rab10_Rab13_like	7..173	CDD:206659	74/162 (46%)
rab44	XP_689291.6	EIN3	<1419..>1534	CDD:296674
		RAB	2218..2380	CDD:197555	74/162 (46%)
		Rab	2218..2375	CDD:206640	72/157 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0078
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900