DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rab10 and rab3b

DIOPT Version :9

Sequence 1:	NP_523419.1	Gene:	Rab10 / 33025	FlyBaseID:	FBgn0015789	Length:	204	Species:	Drosophila melanogaster
Sequence 2:	XP_685654.3	Gene:	rab3b / 557482	ZFINID:	ZDB-GENE-050208-660	Length:	217	Species:	Danio rerio

Alignment Length:	210	Identity:	97/210 - (46%)
Similarity:	140/210 - (66%)	Gaps:	18/210 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 KTYDLLFKLLLIGDSGVGKTCILFRFSDDAFTSTFISTIGIDFKIKTVELRGKKIKLQIWDTAGQ 68
            :.:|.:||||:||:|.||||..|||::||:|:|:|:||:|||||:|||....|::||||||||||
Zfish    16 QNFDYMFKLLIIGNSSVGKTSFLFRYADDSFSSSFVSTVGIDFKVKTVYRNDKRVKLQIWDTAGQ 80

  Fly    69 ERFHTITTSYYRGAMGIMLVYDITNEKSFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVN 133
            ||:.||||:|||||||.:|:||||||:|:..:..|...|..::.::.:.:::||||||.::|||.
Zfish    81 ERYRTITTAYYRGAMGFILMYDITNEESYNAVQDWATQIKTYSWDNAQVILVGNKCDMDEERVVP 145

  Fly   134 KERGEAIAREHGIRFMETSAKSNINIERAFCELAEAILDKTSGRESAENQERVIID--------- 189
            .|:|:.:|.:.|..:.|.|||.|||:.:.|..|.:.|..|.|        |||.::
Zfish   146 FEKGKHLADQLGFEYYEASAKENINVRQVFERLVDIICVKMS--------ERVDVEPPMVTGAKT 202

  Fly   190 RRNQEKAPGY-SKCC 203
            .|..:|.|.. ..||
Zfish   203 TRLTDKPPQLPQNCC 217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab10	NP_523419.1	Rab8_Rab10_Rab13_like	7..173	CDD:206659	87/165 (53%)
rab3b	XP_685654.3	P-loop_NTPase	21..185	CDD:304359	86/163 (53%)
rab3b	XP_685654.3	RAB	22..182	CDD:197555	85/159 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1426655at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920