DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab10 and rab12

DIOPT Version :9

Sequence 1:	NP_523419.1	Gene:	Rab10 / 33025	FlyBaseID:	FBgn0015789	Length:	204	Species:	Drosophila melanogaster
Sequence 2:	NP_001018466.1	Gene:	rab12 / 553657	ZFINID:	ZDB-GENE-050522-555	Length:	235	Species:	Danio rerio

Alignment Length:	203	Identity:	93/203 - (45%)
Similarity:	138/203 - (67%)	Gaps:	6/203 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 DLLFKLLLIGDSGVGKTCILFRFSDDAFTSTFISTIGIDFKIKTVELRGKKIKLQIWDTAGQERF 71
            |...::::||..|||||.::.||:||.|.....||:|:||||||||||||||:||||||||||||
Zfish    33 DYKLQVIIIGSRGVGKTSLMERFTDDTFCEACKSTVGVDFKIKTVELRGKKIRLQIWDTAGQERF 97

  Fly    72 HTITTSYYRGAMGIMLVYDITNEKSFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVNKER 136
            ::||::|||||.||:||||||.:::||::.||::.||::|:||.|.:::|||.|....|.:::::
Zfish    98 NSITSAYYRGAKGIVLVYDITKQETFEDLPKWMKMIDKYASEDAELLLVGNKLDCESDRAISRQQ 162

  Fly   137 GEAIA-REHGIRFMETSAKSNINIERAFCELAEAILDKTSGRESAENQERVIIDRRNQ-----EK 195
            .|..| |..|:||.|.|||.|.|::..|.:|.:.||.|......::.....::..:.:     |.
Zfish   163 AERFASRISGMRFCEASAKDNFNVDEIFLKLVDDILSKMPLEVPSKELSNSVLSLQPEPEIPPEL 227

  Fly   196 APGYSKCC 203
            .|...:||
Zfish   228 PPPRMRCC 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab10	NP_523419.1	Rab8_Rab10_Rab13_like	7..173	CDD:206659	88/166 (53%)
rab12	NP_001018466.1	Rab12	36..235	CDD:206699	90/198 (45%)
rab12	NP_001018466.1	RAB	36..200	CDD:197555	87/163 (53%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0078
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810