DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab10 and rab35b

DIOPT Version :9

Sequence 1:	NP_523419.1	Gene:	Rab10 / 33025	FlyBaseID:	FBgn0015789	Length:	204	Species:	Drosophila melanogaster
Sequence 2:	NP_001003548.1	Gene:	rab35b / 445154	ZFINID:	ZDB-GENE-040801-62	Length:	201	Species:	Danio rerio

Alignment Length:	202	Identity:	95/202 - (47%)
Similarity:	140/202 - (69%)	Gaps:	5/202 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 KTYDLLFKLLLIGDSGVGKTCILFRFSDDAFTSTFISTIGIDFKIKTVELRGKKIKLQIWDTAGQ 68
            :.||.|||||:||||||||:.:|.||:|:.|:.::|:|||:||||:||||.|:|:||||||||||
Zfish     3 RDYDHLFKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVELNGEKVKLQIWDTAGQ 67

  Fly    69 ERFHTITTSYYRGAMGIMLVYDITNEKSFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVN 133
            |||.|||::||||..|:::|||:|:.:||.|:.:||..|:::. :||.::::|||.|..:.:||.
Zfish    68 ERFRTITSTYYRGTHGVVVVYDVTSAESFVNVKRWLHEINQNC-DDVCRILVGNKNDDPNSKVVE 131

  Fly   134 KERGEAIAREHGIRFMETSAKSNINIERAFCELAEAIL--DKTSGRESAENQERVIIDRRNQEKA 196
            ....:..|.:.||...|||||.|:|:|..|..:.|.:|  .|.|..:..:.|:..:|..:...|.
Zfish   132 TNDAQKFAEQMGISLFETSAKENVNVEEMFNCITELVLRAKKESVAKQQQQQQNDVIKLKQNSKR 196

  Fly   197 PGYSKCC 203
            .  .|||
Zfish   197 K--KKCC 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab10	NP_523419.1	Rab8_Rab10_Rab13_like	7..173	CDD:206659	86/167 (51%)
rab35b	NP_001003548.1	P-loop_NTPase	3..201	CDD:304359	93/200 (47%)
rab35b	NP_001003548.1	RAB	9..170	CDD:197555	83/161 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910