DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab10 and Rab44

DIOPT Version :9

Sequence 1:	NP_523419.1	Gene:	Rab10 / 33025	FlyBaseID:	FBgn0015789	Length:	204	Species:	Drosophila melanogaster
Sequence 2:	NP_001351777.1	Gene:	Rab44 / 442827	MGIID:	3045302	Length:	973	Species:	Mus musculus

Alignment Length:	164	Identity:	64/164 - (39%)
Similarity:	100/164 - (60%)	Gaps:	0/164 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 DLLFKLLLIGDSGVGKTCILFRFSDDAFTSTFISTIGIDFKIKTVELRGKKIKLQIWDTAGQERF 71
            |.|:.::.:|||.||||..|.....|||.:...:|:|:||::|.:.:..|...||:||||||||:
Mouse   783 DYLYHVVFLGDSNVGKTSFLHLLHHDAFATGLTATVGVDFRVKNLLVDNKTFALQLWDTAGQERY 847

  Fly    72 HTITTSYYRGAMGIMLVYDITNEKSFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVNKER 136
            |::|....|.|.|::|:||:|:::||.::..||..:.:...|.|..::||||.|..::|.|..|.
Mouse   848 HSLTRQLLRKAEGVVLMYDVTSQESFTHVRYWLDCLQDAGVEGVAMVLLGNKMDCEEERQVPTEA 912

  Fly   137 GEAIAREHGIRFMETSAKSNINIERAFCELAEAI 170
            |..:|:|.|:.|.|.||....||......||.::
Mouse   913 GRRLAQELGVSFGECSAALGHNILEPMMNLARSL 946

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab10	NP_523419.1	Rab8_Rab10_Rab13_like	7..173	CDD:206659	64/164 (39%)
Rab44	NP_001351777.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..42
		EF-hand_7	45..101	CDD:372618
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	112..140
		SMC_prok_B	<173..353	CDD:274008
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	319..368
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	421..481
		PHA03247	<425..783	CDD:223021	64/164 (39%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	493..708
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	724..779
		Rab	788..944	CDD:206640	61/155 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0078
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900