DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab10 and Rab40b

DIOPT Version :9

Sequence 1:	NP_523419.1	Gene:	Rab10 / 33025	FlyBaseID:	FBgn0015789	Length:	204	Species:	Drosophila melanogaster
Sequence 2:	NP_001100546.1	Gene:	Rab40b / 303754	RGDID:	1305663	Length:	279	Species:	Rattus norvegicus

Alignment Length:	168	Identity:	79/168 - (47%)
Similarity:	104/168 - (61%)	Gaps:	1/168 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 KTYDLLFKLLLIGDSGVGKTCILFRFSDDAFTSTFISTIGIDFKIKTVELRGKKIKLQIWDTAGQ 68
            :.||.|.|.||:|||.|||..||....|.|..|.:....|||.|..|:.|.|:::|||:|||:||
  Rat    10 RAYDFLLKFLLVGDSDVGKGEILASLQDGAAESPYGHPAGIDHKTTTILLDGRRVKLQLWDTSGQ 74

  Fly    69 ERFHTITTSYYRGAMGIMLVYDITNEKSFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVN 133
            .||.||..||.|||.|::|||||.|..||:.|.:|::.||||| ..|.|:::||:..:..||.|.
  Rat    75 GRFCTIFRSYSRGAQGVILVYDIANRWSFDGINRWIKEIDEHA-PGVPKILVGNRLHLAFKRQVP 138

  Fly   134 KERGEAIAREHGIRFMETSAKSNINIERAFCELAEAIL 171
            .|:.:|.|...|:.|.|.|...|.||..:|.|||..:|
  Rat   139 TEQAQAYAERLGVTFFEVSPLCNFNITESFTELARIVL 176

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab10	NP_523419.1	Rab8_Rab10_Rab13_like	7..173	CDD:206659	78/165 (47%)
Rab40b	NP_001100546.1	Rab40	10..279	CDD:133321	79/168 (47%)
Rab40b	NP_001100546.1	SOCS_Rab40	188..230	CDD:239711
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0078
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810