DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab10 and rab-10

DIOPT Version :9

Sequence 1:	NP_523419.1	Gene:	Rab10 / 33025	FlyBaseID:	FBgn0015789	Length:	204	Species:	Drosophila melanogaster
Sequence 2:	NP_491857.1	Gene:	rab-10 / 266836	WormBaseID:	WBGene00004273	Length:	201	Species:	Caenorhabditis elegans

Alignment Length:	203	Identity:	146/203 - (71%)
Similarity:	172/203 - (84%)	Gaps:	2/203 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAKKTYDLLFKLLLIGDSGVGKTCILFRFSDDAFTSTFISTIGIDFKIKTVELRGKKIKLQIWDT 65
            ||::.||:||||||||||||||||||:|||||||.:||||||||||||||:||:|||||||||||
Worm     1 MARRPYDMLFKLLLIGDSGVGKTCILYRFSDDAFNTTFISTIGIDFKIKTIELKGKKIKLQIWDT 65

  Fly    66 AGQERFHTITTSYYRGAMGIMLVYDITNEKSFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKR 130
            ||||||||||||||||||||||||||||.|||:||.||||||||||:|||.||||||||||:|:|
Worm    66 AGQERFHTITTSYYRGAMGIMLVYDITNAKSFDNIAKWLRNIDEHASEDVVKMILGNKCDMSDRR 130

  Fly   131 VVNKERGEAIAREHGIRFMETSAKSNINIERAFCELAEAILDKTSGRESAENQERVIIDRRNQEK 195
            ||::||||.||::|||.|.|||||.|::::.||.:||||||.|..  :|.:.|.|..::....::
Worm   131 VVSRERGEKIAQDHGISFHETSAKLNVHVDTAFYDLAEAILAKMP--DSTDEQSRDTVNPVQPQR 193

  Fly   196 APGYSKCC 203
            ......||
Worm   194 QSSSGGCC 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab10	NP_523419.1	Rab8_Rab10_Rab13_like	7..173	CDD:206659	137/165 (83%)
rab-10	NP_491857.1	Rab8_Rab10_Rab13_like	7..173	CDD:206659	137/165 (83%)
rab-10	NP_491857.1	RAB	10..173	CDD:197555	135/162 (83%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164609
Domainoid	1	1.000	279	1.000	Domainoid score	I901
eggNOG	1	0.900	-	-		E1_KOG0078
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H41111
Inparanoid	1	1.050	299	1.000	Inparanoid score	I1641
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1426655at2759
OrthoFinder	1	1.000	-	-		FOG0000502
OrthoInspector	1	1.000	-	-		oto17373
orthoMCL	1	0.900	-	-		OOG6_107709
Panther	1	1.100	-	-	LDO	PTHR47980
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1998
SonicParanoid	1	1.000	-	-		X312
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	13	12.830