DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rab10 and rab-1

DIOPT Version :9

Sequence 1:	NP_523419.1	Gene:	Rab10 / 33025	FlyBaseID:	FBgn0015789	Length:	204	Species:	Drosophila melanogaster
Sequence 2:	NP_503397.1	Gene:	rab-1 / 178620	WormBaseID:	WBGene00004266	Length:	205	Species:	Caenorhabditis elegans

Alignment Length:	200	Identity:	109/200 - (54%)
Similarity:	147/200 - (73%)	Gaps:	4/200 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 YDLLFKLLLIGDSGVGKTCILFRFSDDAFTSTFISTIGIDFKIKTVELRGKKIKLQIWDTAGQER 70
            ||.||||||||||||||:|:|.||:||.:|.::|||||:||||:|:||.||.|||||||||||||
Worm     8 YDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQER 72

  Fly    71 FHTITTSYYRGAMGIMLVYDITNEKSFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVNKE 135
            |.|||:||||||.||::|||||::::|.|:.:||:.||.:|.|:|.|:::|||||:|.||.|..:
Worm    73 FRTITSSYYRGAHGIIVVYDITDQETFNNVKQWLQEIDRYACENVNKLLVGNKCDLTAKRAVETQ 137

  Fly   136 RGEAIAREHGIRFMETSAKSNINIERAFCELAEAILDKTSGRESAENQE--RVIIDRRNQEKAPG 198
            ..:..|.:.||.|:||||||:.|:|:||..:|..|..:....:.|....  |:...:..|:|..|
Worm   138 AAQDYAGQLGIPFLETSAKSSTNVEQAFLTMASEIKSRMGPVQGAGGAPGVRITGSQPVQDKKSG 202

  Fly   199 YSKCC 203
              .||
Worm   203 --GCC 205

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rab10	NP_523419.1	Rab8_Rab10_Rab13_like	7..173	CDD:206659	101/165 (61%)
rab-1	NP_503397.1	Rab1_Ypt1	10..175	CDD:206661	100/164 (61%)
rab-1	NP_503397.1	RAB	12..175	CDD:197555	99/162 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910