Protein Alignment Rab10 and RAB3C

DIOPT Version :10

• Sequence 1: NP_523419.1
• Gene: Rab10 / 33025
• FlyBaseID: FBgn0015789
• Length: 204
• Species: Drosophila melanogaster
• Sequence 2: NP_612462.1
• Gene: RAB3C / 115827
• HGNCID: 30269
• Length: 227
• Species: Homo sapiens
• Alignment Length: 204
• Identity: 103/204 - (50%)
• Similarity: 143/204 - (70%)
• Gaps: 5/204 - (2%)

  Fly     4 KTYDLLFKLLLIGDSGVGKTCILFRFSDDAFTSTFISTIGIDFKIKTVELRGKKIKLQIWDTAGQ 68
            :.:|.:||||:||:|.||||..|||::||:|||.|:||:|||||:|||....|:|||||||||||
Human    25 QNFDYMFKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQ 89

  Fly    69 ERFHTITTSYYRGAMGIMLVYDITNEKSFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVN 133
            ||:.||||:|||||||.:|:||||||:||..:..|...|..::.::.:.:::||||||.|:||::
Human    90 ERYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILVGNKCDMEDERVIS 154

  Fly   134 KERGEAIAREHGIRFMETSAKSNINIERAFCELAEAILDKTSGRESAENQERVIIDRRN---QEK 195
            .|||:.:..:.|..|.|||||.|||:::.|..|.:.|.||.|  ||.|....:...::|   :|.
Human   155 TERGQHLGEQLGFEFFETSAKDNINVKQTFERLVDIICDKMS--ESLETDPAITAAKQNTRLKET 217

  Fly   196 APGYSKCCA 204
            .|.....||
Human   218 PPPPQPNCA 226

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab10	NP_523419.1	Rab8_Rab10_Rab13_like	7..173	CDD:206659	92/165 (56%)
RAB3C	NP_612462.1	Rab3	30..194	CDD:206657	91/163 (56%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P10949	53..66		8/12 (67%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P10949	86..104		14/17 (82%)