DRSC/TRiP Functional Genomics Resources

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Protein Alignment Rab10 and Rab1b

DIOPT Version :9

Sequence 1:NP_523419.1 Gene:Rab10 / 33025 FlyBaseID:FBgn0015789 Length:204 Species:Drosophila melanogaster
Sequence 2:NP_001103449.1 Gene:Rab1b / 100126191 RGDID:1642882 Length:201 Species:Rattus norvegicus


Alignment Length:200 Identity:109/200 - (54%)
Similarity:149/200 - (74%) Gaps:5/200 - (2%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 YDLLFKLLLIGDSGVGKTCILFRFSDDAFTSTFISTIGIDFKIKTVELRGKKIKLQIWDTAGQER 70
            ||.||||||||||||||:|:|.||:||.:|.::|||||:||||:|:||.||.|||||||||||||
  Rat     5 YDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQER 69

  Fly    71 FHTITTSYYRGAMGIMLVYDITNEKSFENIVKWLRNIDEHANEDVEKMILGNKCDMTDKRVVNKE 135
            |.|||:||||||.||::|||:|:::|:.|:.:||:.||.:|:|:|.|:::|||.|:|.|:||:..
  Rat    70 FRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKLLVGNKSDLTTKKVVDNT 134

  Fly   136 RGEAIAREHGIRFMETSAKSNINIERAFCELAEAILDKTSGRESAENQER--VIIDRRNQEKAPG 198
            ..:..|...|:.|:|||||:..|:|:||..:| |.:.|..|..:|...||  :.||....:.|.|
  Rat   135 TAKEFADSLGVPFLETSAKNATNVEQAFMTMA-AEIKKRMGPGAASGGERPNLKIDSTPVKSASG 198

  Fly   199 YSKCC 203
              .||
  Rat   199 --GCC 201

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rab10NP_523419.1 Rab8_Rab10_Rab13_like 7..173 CDD:206659 97/165 (59%)
Rab1bNP_001103449.1 Rab1_Ypt1 7..172 CDD:206661 96/165 (58%)
Effector region. /evidence=ECO:0000255 37..45 5/7 (71%)
Switch 2 region, required for interaction with REP1/CHM. /evidence=ECO:0000250|UniProtKB:Q9H0U4 64..83 16/18 (89%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 173..201 8/29 (28%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.910

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