Protein Alignment CG17068 and BTBD1

DIOPT Version :9

• Sequence 1: NP_608379.1
• Gene: CG17068 / 33024
• FlyBaseID: FBgn0031098
• Length: 694
• Species: Drosophila melanogaster
• Sequence 2: NP_079514.1
• Gene: BTBD1 / 53339
• HGNCID: 1120
• Length: 482
• Species: Homo sapiens
• Alignment Length: 555
• Identity: 128/555 - (23%)
• Similarity: 198/555 - (35%)
• Gaps: 161/555 - (29%)

  Fly     4 DWQNGLTELKDRGQYLLHSEKWADCRFLVG-------SSPTQRLIAGHKLLLAMASPVFERMFYG 61
            :||.....||:|..:|.:||..:|.||::|       :...|| |..|:.:||..|.||:.||.|
Human    47 NWQATKASLKERFAFLFNSELLSDVRFVLGKGRGAAAAGGPQR-IPAHRFVLAAGSAVFDAMFNG 110

  Fly    62 NLPDKTDPIVIPDVQPEAFEAMLEYIYTDRITIGSFDKACELCYVAKKYMLPHVVTRCTHFLWAD 126
            .:...:..|.:|||:|.||.|:|.::|:|.:.||. :......|.||||.:|.:...|..||...
Human   111 GMATTSAEIELPDVEPAAFLALLRFLYSDEVQIGP-ETVMTTLYTAKKYAVPALEAHCVEFLTKH 174

  Fly   127 LSPKNACRAYEFAKLFDEPRLMQSSMDLIAANTREVLSDPSFLDIEVSTLMAILDQNRLNIDSEL 191
            |...||......|:|||||:|....:|.|..:|.:.:|...|.||::.||.|:|:::.|:| .|.
Human   175 LRADNAFMLLTQARLFDEPQLASLCLDTIDKSTMDAISAEGFTDIDIDTLCAVLERDTLSI-RES 238

  Fly   192 DLFNCLLKFASERGILNESGQEETASGGQVLTKESPDNAAGHVLVEEIKMEPDVAAMVQHMHQDD 256
            .||..::::|
Human   239 RLFGAVVRWA------------------------------------------------------- 248

  Fly   257 EADSFETDAGMASTSSAAAAAAAAPTAASPPLDVASGSDDLVIIDSDASADAAANMINIMDAQRT 321
            ||:                       .....|.|..|:...|
Human   249 EAE-----------------------CQRQQLPVTFGNKQKV----------------------- 267

  Fly   322 ILDGAMLRQAVKKIRFLTMTPQQFAEGPARSKLLQQHEALSILIK-----------ISSPSLNDC 375
                  |.:|:..|||..||.::||.|||:|.:|...|.:::.:.           |..|..  |
Human   268 ------LGKALSLIRFPLMTIEEFAAGPAQSGILSDREVVNLFLHFTVNPKPRVEYIDRPRC--C 324

  Fly   376 HMPEGFCVSRSTRNFYESGHRHAQRELSSSYRTGAAPSGVCFPGPGPAVRSGGPSGGGMMMGI-- 438
            ...:..|::|    |.:...|......|...|. .....:...|.|......||:...:.:.|
Human   325 LRGKECCINR----FQQVESRWGYSGTSDRIRF-TVNRRISIVGFGLYGSIHGPTDYQVNIQIIE 384

  Fly   439 ---APRFGSVGTGFGFAGEELVIRP--PEPVGVPPDAAPAPAPLRCFGEGYESGAPVPAPANDDD 498
               ....|...|||...|.....|.  .||:.:.|:..            |.:.|.:..|  |..
Human   385 YEKKQTLGQNDTGFSCDGTANTFRVMFKEPIEILPNVC------------YTACATLKGP--DSH 435

  Fly   499 GGDRGA-----PAPAGGAAAGGAGSAAGNSHNDMV 528
            .|.:|.     ..||.........|:.||::...:
Human   436 YGTKGLKKVVHETPAASKTVFFFFSSPGNNNGTSI 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17068	NP_608379.1	BTB	19..123	CDD:279045	39/110 (35%)
		BTB	27..127	CDD:197585	38/106 (36%)
		BACK	136..>199	CDD:197943	23/62 (37%)
BTBD1	NP_079514.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..36
		BTB	62..175	CDD:306997	41/114 (36%)
		BACK	187..286	CDD:197943	37/206 (18%)
		PHR	334..480	CDD:311801	30/156 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2075
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45774
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	4	3.870