DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17068 and kbtbd4

DIOPT Version :9

Sequence 1:	NP_608379.1	Gene:	CG17068 / 33024	FlyBaseID:	FBgn0031098	Length:	694	Species:	Drosophila melanogaster
Sequence 2:	NP_956503.1	Gene:	kbtbd4 / 393178	ZFINID:	ZDB-GENE-040426-937	Length:	522	Species:	Danio rerio

Alignment Length:	268	Identity:	55/268 - (20%)
Similarity:	99/268 - (36%)	Gaps:	54/268 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MDIDWQNGLTELKDRGQYLLHSEKWADCRFLVGSSPTQRLIAGHKLLLAMASPVFERMFYGNLPD 65
            ||:..::||               :||....|.|...|.    |:|:|:..|..|..||..||.:
Zfish    39 MDLCLEDGL---------------FADVIVTVDSKEFQL----HRLVLSAQSSFFRSMFTSNLRE 84

  Fly    66 KTD-PIVIPDVQPEAFEAMLEYIYTDRITIGSFDKACELCYVAKKYMLPHVVTRCTHFLWADLSP 129
            ..| .|.:.||....|:::::|||...|.:...|.. :...:|..|.|..:...|:.||...:..
Zfish    85 AYDRNIELKDVSATVFQSLVDYIYHGMIKLRVEDLQ-DTYEMADMYQLTALFEECSRFLSRTVDV 148

  Fly   130 KNACRAYEFAKLFDEPRLMQSSMDLIAANTREVLSDPSFLDIEVSTLMAI--------------- 179
            :|..:....|....:..|..::......:..::.....||::.:..||.|
Zfish   149 RNCLQVMWLADRHSDQELYTAAKHCAKIHLVQLHQTDEFLNLPLCLLMDIIKDGVPSSQNPTAAI 213

  Fly   180 ---LDQNRLNIDSELDLFNCLLKFASERGILNESGQEETASGGQVLTKESPDNAAGHVLVEEIKM 241
               ::.|::..:...|:....||...|:..:...|:|:|.:               |.|...:..
Zfish   214 ESWINHNKVEREEYSDMLLDSLKEIGEKVHIYLIGKEDTRT---------------HSLAVSLHC 263

  Fly   242 EPDVAAMV 249
            :.|.|..|
Zfish   264 DEDHAISV 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17068	NP_608379.1	BTB	19..123	CDD:279045	28/104 (27%)
		BTB	27..127	CDD:197585	29/100 (29%)
		BACK	136..>199	CDD:197943	9/80 (11%)
kbtbd4	NP_956503.1	BTB	39..142	CDD:279045	32/122 (26%)
		BTB	50..142	CDD:197585	27/96 (28%)
		BACK	151..247	CDD:197943	12/95 (13%)
		KELCH repeat	283..318	CDD:276965
		KELCH repeat	322..369	CDD:276965
		KELCH repeat	372..421	CDD:276965
		KELCH repeat	424..471	CDD:276965
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576645
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930