DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17068 and Kbtbd4

DIOPT Version :9

Sequence 1:	NP_608379.1	Gene:	CG17068 / 33024	FlyBaseID:	FBgn0031098	Length:	694	Species:	Drosophila melanogaster
Sequence 2:	XP_017447204.1	Gene:	Kbtbd4 / 311185	RGDID:	1310234	Length:	553	Species:	Rattus norvegicus

Alignment Length:	255	Identity:	55/255 - (21%)
Similarity:	100/255 - (39%)	Gaps:	24/255 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 KDRG----------QYLLHSEKWADCRFLVGSSPTQRLIAGHKLLLAMASPVFERMFYGNLPDKT 67
            |||.          :..|..|.:||....|.....|.    |:|:|:..|..|..||..||.:..
  Rat    57 KDRSHSGRVAQGIMKLCLEEELFADVTISVEGREFQL----HRLVLSAQSCFFRSMFTSNLKEAH 117

  Fly    68 D-PIVIPDVQPEAFEAMLEYIYTDRITIGSFDKACELCYVAKKYMLPHVVTRCTHFLWADLSPKN 131
            : .||:.||....|:.:::|||...:.:.: |:..|:..|:..|.|..:...|:.||...:...|
  Rat   118 NRVIVLQDVSESVFQLLVDYIYHGTVKLRA-DELQEIYEVSDMYQLTSLFEECSRFLARTVQVGN 181

  Fly   132 ACRAYEFAKLFDEPRLMQSSMDLIAANTREVLSDPSFLDIEVSTLMAILDQNRLNIDSELDLFNC 196
            ..:....|....:|.|..::......:..::.|...||.:....|..|:........:..:..:.
  Rat   182 CLQVMWLADRHSDPELYTAAKHCAKTHLAQLQSTEEFLHLPHHLLTDIISDGVPCSQNPTEAIDA 246

  Fly   197 LLKFASERGILNESGQEETASGGQVLTKESPDNAAGHVLVEEIKMEPDVAAMVQHMHQDD 256
            .:.|       |:..:|..|...:...||..:|...:::.:|......:|..: |..:||
  Rat   247 WINF-------NKEEREAFAESLRTSLKEIGENVHIYLIGKESSRTHSLAVSL-HCAEDD 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17068	NP_608379.1	BTB	19..123	CDD:279045	29/104 (28%)
		BTB	27..127	CDD:197585	28/100 (28%)
		BACK	136..>199	CDD:197943	8/62 (13%)
Kbtbd4	XP_017447204.1	BTB_POZ_KBTBD4	48..187	CDD:349581	35/134 (26%)
		PHA03098	82..514	CDD:222983	48/230 (21%)
		BACK_KBTBD4	177..264	CDD:350556	13/93 (14%)
		KELCH repeat	314..349	CDD:276965
		KELCH repeat	353..400	CDD:276965
		KELCH repeat	403..449	CDD:276965
		KELCH repeat	457..502	CDD:276965
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337448
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840