DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17068 and BTBD11

DIOPT Version :9

Sequence 1:	NP_608379.1	Gene:	CG17068 / 33024	FlyBaseID:	FBgn0031098	Length:	694	Species:	Drosophila melanogaster
Sequence 2:	NP_001018082.1	Gene:	BTBD11 / 121551	HGNCID:	23844	Length:	1104	Species:	Homo sapiens

Alignment Length:	183	Identity:	40/183 - (21%)
Similarity:	74/183 - (40%)	Gaps:	20/183 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LTELKDR-----GQYLLHSEKWADCRFLVGSSPTQRLIAGHKLLLAMASPVFERMFYGNLPDKTD 68
            |||:|.:     ..:.|::::.:|..|||...|    ...||:||..|||.|:.:......:...
Human   901 LTEIKRKQTSRLDPHFLNNKEMSDVTFLVEGRP----FYAHKVLLFTASPRFKALLSSKPTNDGT 961

  Fly    69 PIVIPDVQPEAFEAMLEYIY---TDRITIGSFDKACELCYVAKKYMLPHVVTRCTHFLWADLSPK 130
            .|.|..|:...|:.:::|:|   .:.:.|.: ::..||...||.:.|..:...|.......::..
Human   962 CIEIGYVKYSIFQLVMQYLYYGGPESLLIKN-NEIMELLSAAKFFQLEALQRHCEIICAKSINTD 1025

  Fly   131 NACRAYEFAKLFDEPRLMQSSMDLIAANTREVLSDPSFLDIEVSTLMAILDQN 183
            |....|..||......|..........|...::.:.:|..:       :.|:|
Human  1026 NCVDIYNHAKFLGVTELSAYCEGYFLKNMMVLIENEAFKQL-------LYDKN 1071

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17068	NP_608379.1	BTB	19..123	CDD:279045	27/106 (25%)
		BTB	27..127	CDD:197585	26/102 (25%)
		BACK	136..>199	CDD:197943	8/48 (17%)
BTBD11	NP_001018082.1	H2A	200..>244	CDD:305064
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	260..301
		Ank_4	<580..624	CDD:290365
		ANK	598..751	CDD:238125
		ANK 1	603..632
		ANK repeat	606..647	CDD:293786
		Ank_2	608..716	CDD:289560
		ANK repeat	649..680	CDD:293786
		ANK 2	649..678
		ANK repeat	682..712	CDD:293786
		ANK 3	687..716
		Ank_2	692..>752	CDD:289560
		ANK 4	730..759
		ANK 5	825..854
		BTB	915..1018	CDD:279045	27/107 (25%)
		BTB	924..1022	CDD:197585	26/102 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143718
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930