DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment obst-A and AgaP_AGAP000989

DIOPT Version :9

Sequence 1:	NP_001245778.1	Gene:	obst-A / 33022	FlyBaseID:	FBgn0031097	Length:	237	Species:	Drosophila melanogaster
Sequence 2:	XP_309184.5	Gene:	AgaP_AGAP000989 / 1270484	VectorBaseID:	AGAP000989	Length:	234	Species:	Anopheles gambiae

Alignment Length:	238	Identity:	159/238 - (66%)
Similarity:	185/238 - (77%)	Gaps:	5/238 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKLFLCAIAVTLCVATTVSAANFECPKPNGQFADEVQCDKFYVCDDGVAKAKLCPDGLVFDPLNR 65
            |:..|...|.|:   ..:.|.:|:||..:||:.|.|||||||.|.||.|..:||||||||||..|
Mosquito     1 MRYILVVFAATV---ACIYAQSFKCPPKDGQYEDPVQCDKFYECVDGRATERLCPDGLVFDPTIR 62

  Fly    66 KFNKCDQPFNVDCEDRTELQEPKSSKYCPRKNGFFAHPDPAVCNIFYNCIEGDALETKCTVGLHF 130
            |.|||||||||||.:|.|||.|:.:..|||:|||||||||||||:|||||||:|.|..||.||||
Mosquito    63 KINKCDQPFNVDCGNREELQPPRGNNLCPRRNGFFAHPDPAVCNVFYNCIEGEANEITCTAGLHF 127

  Fly   131 DEYSGTCVWPDTAKREGCNPEQRTS-ETGFVCPKDQPKTDDRGQVVTHPKYPHPTDCQKFYVCLN 194
            |||:||||||:.|.|:||||...:. ..||.||||| |||:.||||.||||.||||||:||||||
Mosquito   128 DEYTGTCVWPNDAGRQGCNPGANSKIFDGFTCPKDQ-KTDEAGQVVAHPKYAHPTDCQRFYVCLN 191

  Fly   195 GEDPRDLGCQLGEVYNDATEMCDAPENVPGCEDWYKDVDDKKD 237
            |.:|||||||:|||||:.||.|||||||||||||||:.|:||:
Mosquito   192 GVEPRDLGCQVGEVYNEETERCDAPENVPGCEDWYKESDEKKN 234

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
obst-A	NP_001245778.1	CBM_14	27..77	CDD:366726	34/49 (69%)
		CBM_14	95..143	CDD:366726	38/47 (81%)
		CBM_14	180..225	CDD:366726	36/44 (82%)
AgaP_AGAP000989	XP_309184.5	ChtBD2	20..70	CDD:214696	33/49 (67%)
		CBM_14	92..140	CDD:279884	38/47 (81%)
		CBM_14	177..222	CDD:279884	36/44 (82%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	102	1.000	Domainoid score	I13048
eggNOG	1	0.900	-	-		E1_294X7
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H15912
Inparanoid	1	1.050	358	1.000	Inparanoid score	I4424
OMA	1	1.010	-	-		QHG28453
OrthoDB	1	1.010	-	-		D106606at50557
OrthoFinder	1	1.000	-	-		FOG0004529
OrthoInspector	1	1.000	-	-		oto109833
Panther	1	1.100	-	-	LDO	PTHR23301
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X15868
TreeFam	1	0.960	-	-
	13	12.940