DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AnxB10 and ANN6

DIOPT Version :9

Sequence 1:	NP_001162804.1	Gene:	AnxB10 / 33019	FlyBaseID:	FBgn0000084	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	NP_196584.1	Gene:	ANN6 / 830886	AraportID:	AT5G10220	Length:	318	Species:	Arabidopsis thaliana

Alignment Length:	321	Identity:	109/321 - (33%)
Similarity:	171/321 - (53%)	Gaps:	23/321 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 PVPTVKDAAPFDASQDAQVLRAAMKGFGTDEQEIIDVLVGRSNQQRQTIKAVYEAEFERDLVDDL 69
            |:|          .:|::.|..|.||:||:|..||.:|..|:..||..|:|||.|.:.:||:.:|
plant    11 PLP----------EEDSEQLHKAFKGWGTNEGMIISILAHRNATQRSFIRAVYAANYNKDLLKEL 65

  Fly    70 KDELGGKFEDVIVGLMMPPVEYLCKQLHAAMAGIGTEEAT-----LVEILCTKTNEEMAQIVAVY 129
            ..||.|.||.|::...:.|.|     ..|.:|...|:..|     ||||.||:.:.|..:....|
plant    66 DGELSGDFERVVMLWTLDPTE-----RDAYLANESTKLFTKNIWVLVEIACTRPSLEFFKTKQAY 125

  Fly   130 EERYQRPLAEQMCSETSGFFRRLLTLIVTGVR-DGLDTPVDVGQAKEQAAQLYSAGEAKLGTDEE 193
            ..||:..|.|.:...|||..|:||..:|:..| ||....|:|..|:.:|..|:.....|..|||:
plant   126 HVRYKTSLEEDVAYHTSGNIRKLLVPLVSTFRYDGNADEVNVKLARSEAKTLHKKITEKAYTDED 190

  Fly   194 VFNRIMSHASFPQLRLVFEEYKVLSGQTIEQAIKHEMSDELHEAMMAIVECVQSPAAFFANRLYK 258
            :. ||::..|..|:......:|...|.:|.:.:|.:.:|:..:.:...::|:..|..:|...|.:
plant   191 LI-RILTTRSKAQINATLNHFKDKFGSSINKFLKEDSNDDYVQLLKTAIKCLTYPEKYFEKVLRR 254

  Fly   259 AMNGAGTDDATLIRIIVSRSEIDLETIKQEFERIYNRTLHSAVVDAETSGDYKRALTALLG 319
            |:|..|||:..|.|::.:|:|:|||.||:|:.|..:..|..|:.: :||||||..|.||||
plant   255 AINRMGTDEWALTRVVTTRAEVDLERIKEEYLRRNSVPLDRAIAN-DTSGDYKDMLLALLG 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AnxB10	NP_001162804.1	Annexin	19..84	CDD:278615	28/64 (44%)
		Annexin	91..156	CDD:278615	22/69 (32%)
		Annexin	176..241	CDD:278615	15/64 (23%)
		Annexin	251..317	CDD:278615	27/65 (42%)
ANN6	NP_196584.1	Annexin	16..80	CDD:278615	28/63 (44%)
		Annexin	104..152	CDD:295376	18/47 (38%)
		Annexin	174..234	CDD:295376	15/60 (25%)
		Annexin	247..312	CDD:278615	27/65 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	57	1.000	Domainoid score	I3988
eggNOG	1	0.900	-	-		E1_KOG0819
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	191	1.000	Inparanoid score	I1373
OMA	1	1.010	-	-		QHG54302
OrthoDB	1	1.010	-	-		D856254at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm965
orthoMCL	1	0.900	-	-		OOG6_124229
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X76
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.740