DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AnxB10 and anxa13

DIOPT Version :9

Sequence 1:	NP_001162804.1	Gene:	AnxB10 / 33019	FlyBaseID:	FBgn0000084	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	NP_001015787.1	Gene:	anxa13 / 548504	XenbaseID:	XB-GENE-979599	Length:	316	Species:	Xenopus tropicalis

Alignment Length:	313	Identity:	132/313 - (42%)
Similarity:	203/313 - (64%)	Gaps:	4/313 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 PTVKDAAPFDASQDAQVLRAAMKGFGTDEQEIIDVLVGRSNQQRQTIKAVYEAEFERDLVDDLKD 71
            ||:|....|||.:||:.:..|.||.||||:.||::|..|::.|||.:|..|:..:.:||...||.
Frog     6 PTIKLHHDFDAERDAKKIYKACKGLGTDEKAIIEILANRTSDQRQELKQKYKTLYGKDLESVLKS 70

  Fly    72 ELGGKFEDVIVGLMMPPVEYLCKQLHAAMAGIGTEEATLVEILCTKTNEEMAQIVAVYEERYQRP 136
            ||.|.||...:.|:..|.|:..::|.:||.|.||.|:.|::||||::|:::......|:..:.|.
Frog    71 ELSGNFEKTALALLDRPCEFDARELRSAMKGAGTNESLLIQILCTRSNQQIKATKEAYKRLFDRD 135

  Fly   137 LAEQMCSETSGFFRRLLTLIVTGVRD-GLDTPVDVGQAKEQAAQLYSAGEAKLGTDEEVFNRIMS 200
            |...:.|||||:||::|..::...|| ||....|:  |.:.|.:||.||||:.||:|..||.|::
Frog   136 LESDIKSETSGYFRKILISLLQANRDEGLSINEDL--AGQDAKRLYEAGEARWGTEESEFNIILA 198

  Fly   201 HASFPQLRLVFEEYKVLSGQTIEQAIKHEMSDELHEAMMAIVECVQSPAAFFANRLYKAMNGAGT 265
            ..::.|||..|:.|::|.|:.|...||.|.|.:|.:|...||:..:....:||.:|||||.||||
Frog   199 TRNYMQLRATFKAYEILHGKDILDVIKSETSGDLKKAYSTIVQVTRDCQGYFAKKLYKAMKGAGT 263

  Fly   266 DDATLIRIIVSRSEIDLETIKQEFERIYNRTLHSAVVDAETSGDYKRALTALL 318
            ::|.||||:|:|:||||:|||:.::::|.::|..| :.::||||:.|.|.|||
Frog   264 NEAMLIRILVTRAEIDLQTIKERYQQLYKKSLGEA-IKSDTSGDFCRLLLALL 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AnxB10	NP_001162804.1	Annexin	19..84	CDD:278615	27/64 (42%)
		Annexin	91..156	CDD:278615	24/64 (38%)
		Annexin	176..241	CDD:278615	27/64 (42%)
		Annexin	251..317	CDD:278615	34/65 (52%)
anxa13	NP_001015787.1	Annexin	18..83	CDD:365936	27/64 (42%)
		Annexin	90..155	CDD:365936	24/64 (38%)
		Annexin	173..235	CDD:365936	26/61 (43%)
		Annexin	249..314	CDD:365936	34/65 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	66	1.000	Domainoid score	I9762
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54302
OrthoDB	1	1.010	-	-		D500720at33208
OrthoFinder	1	1.000	-	-		FOG0000105
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X76
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.930