DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AnxB10 and anxa11

DIOPT Version :9

Sequence 1:	NP_001162804.1	Gene:	AnxB10 / 33019	FlyBaseID:	FBgn0000084	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	NP_001006124.1	Gene:	anxa11 / 448260	XenbaseID:	XB-GENE-958577	Length:	498	Species:	Xenopus tropicalis

Alignment Length:	312	Identity:	144/312 - (46%)
Similarity:	205/312 - (65%)	Gaps:	2/312 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 TVKDAAPFDASQDAQVLRAAMKGFGTDEQEIIDVLVGRSNQQRQTIKAVYEAEFERDLVDDLKDE 72
            |:.|||.|||.:||:|||.||||||||||.||:.|..|||:|||.|...::..:.:||:.|||.|
Frog   186 TITDAANFDALRDAEVLRKAMKGFGTDEQAIIECLGSRSNKQRQQISLSFKTAYGKDLIKDLKSE 250

  Fly    73 LGGKFEDVIVGLMMPPVEYLCKQLHAAMAGIGTEEATLVEILCTKTNEEMAQIVAVYEERYQRPL 137
            |.|.||..|:.:|..|..|...::|.|:.|.||:|..|:|||.:::|..:.:|...|:..|::.|
Frog   251 LSGNFEKTILAMMKTPTLYDAHEIHEAIKGAGTDEECLIEILASRSNAAVHEICNAYKTEYKKTL 315

  Fly   138 AEQMCSETSGFFRRLLTLIVTGVRDGLDTPVDVGQAKEQAAQLYSAGEAKLGTDEEVFNRIMSHA 202
            .:.:.|:|||.|.|||..:..|.||..:. ||:...:....:||:|||.:|||||..||.|:...
Frog   316 EQAIKSDTSGHFLRLLVSLAQGNRDESNN-VDMALVQRDVQELYAAGENRLGTDESKFNAILCTR 379

  Fly   203 SFPQLRLVFEEYKVLSGQTIEQAIKHEMSDELHEAMMAIVECVQSPAAFFANRLYKAMNGAGTDD 267
            |...|..||.||:.:..:.||::|..|||..|...|:|:|:|:::..||||.||||:|.||||.|
Frog   380 SRAHLNAVFSEYQRMCNRDIEKSICREMSGNLENGMLAVVKCLKNTPAFFAERLYKSMKGAGTKD 444

  Fly   268 ATLIRIIVSRSEIDLETIKQEFERIYNRTLHSAVVDAETSGDYKRALTALLG 319
            .|||||:|||||:||..|:.|::|:|.|:|::.:. .:|||||::.|..|.|
Frog   445 KTLIRIMVSRSEVDLLDIRSEYKRMYGRSLYTDIT-GDTSGDYRKILLKLCG 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AnxB10	NP_001162804.1	Annexin	19..84	CDD:278615	36/64 (56%)
		Annexin	91..156	CDD:278615	24/64 (38%)
		Annexin	176..241	CDD:278615	27/64 (42%)
		Annexin	251..317	CDD:278615	37/65 (57%)
anxa11	NP_001006124.1	Cytadhesin_P30	<12..169	CDD:284643
		Annexin	197..262	CDD:395139	36/64 (56%)
		Annexin	269..334	CDD:395139	24/64 (38%)
		Annexin	352..418	CDD:395139	27/65 (42%)
		Annexin	428..493	CDD:395139	37/65 (57%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54302
OrthoDB	1	1.010	-	-		D500720at33208
OrthoFinder	1	1.000	-	-		FOG0000105
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X76
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.930