DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AnxB10 and anxa3a

DIOPT Version :9

Sequence 1:	NP_001162804.1	Gene:	AnxB10 / 33019	FlyBaseID:	FBgn0000084	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	NP_001004632.2	Gene:	anxa3a / 447893	ZFINID:	ZDB-GENE-040912-58	Length:	340	Species:	Danio rerio

Alignment Length:	313	Identity:	128/313 - (40%)
Similarity:	195/313 - (62%)	Gaps:	4/313 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 TVKDAAPFDASQDAQVLRAAMKGFGTDEQEIIDVLVGRSNQQRQTIKAVYEAEFERDLVDDLKDE 72
            |:|..|.|:.|:|...||.|::|.||:|:.:|::|..||:.|:|.|...|....:|.|.:|||.|
Zfish    28 TIKAKANFNVSEDVAALRKAIEGVGTNEKTLIEILTHRSSSQKQEIAKAYRETTKRILANDLKGE 92

  Fly    73 LGGKFEDVIVGLMMPPVEYLCKQLHAAMAGIGTEEATLVEILCTKTNEEMAQIVAVYEERYQRPL 137
            ..|.||.|:|||..|......:.||.|:.|.||:...|:|||.::||:::.::.|.|.|..::.|
Zfish    93 THGNFEKVLVGLARPLAVNDAEWLHEALKGAGTDNNILIEILSSRTNKQIKELSAAYAEETKKTL 157

  Fly   138 AEQMCSETSGFFRRLLTLIVTGVRDGLDTP-VDVGQAKEQAAQLYSAGEAKLGTDEEVFNRIMSH 201
            .:.:.:|.||.:.:.:.|:..|.||  :.| |:|.:|:|.|..||.|||.||||||..|..|:..
Zfish   158 TQALKTEVSGHYGKAIILLAEGARD--ENPSVNVDKAREDAQALYQAGEKKLGTDESKFIEILCK 220

  Fly   202 ASFPQLRLVFEEYKVLSGQTIEQAIKHEMSDELHEAMMAIVECVQSPAAFFANRLYKAMNGAGTD 266
            .||||||....|||..|..|::::|:.|||..|.|.:::||:|..|..|:||.:|.|:|.|||||
Zfish   221 RSFPQLRQTILEYKNFSKNTLQKSIEKEMSGNLEELLVSIVKCAISTPAYFAEKLNKSMKGAGTD 285

  Fly   267 DATLIRIIVSRSEIDLETIKQEFERIYNRTLHSAVVDAETSGDYKRALTALLG 319
            :.||.|::|||.|:|:..|:.|::.:|..:|:.| :.::.||||...|..:.|
Zfish   286 ETTLTRVMVSRGEVDMLDIRAEYKTLYKSSLYKA-ISSDVSGDYADCLKMICG 337

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AnxB10	NP_001162804.1	Annexin	19..84	CDD:278615	27/64 (42%)
		Annexin	91..156	CDD:278615	19/64 (30%)
		Annexin	176..241	CDD:278615	31/64 (48%)
		Annexin	251..317	CDD:278615	28/65 (43%)
anxa3a	NP_001004632.2	Annexin	40..104	CDD:306660	27/63 (43%)
		Annexin	112..176	CDD:306660	19/63 (30%)
		Annexin	195..260	CDD:306660	31/64 (48%)
		Annexin	270..335	CDD:306660	28/65 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0819
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54302
OrthoDB	1	1.010	-	-		D500720at33208
OrthoFinder	1	1.000	-	-		FOG0000105
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X76
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.830