DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AnxB10 and anxa7

DIOPT Version :9

Sequence 1:	NP_001162804.1	Gene:	AnxB10 / 33019	FlyBaseID:	FBgn0000084	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	XP_012821793.2	Gene:	anxa7 / 407959	XenbaseID:	XB-GENE-987772	Length:	536	Species:	Xenopus tropicalis

Alignment Length:	312	Identity:	151/312 - (48%)
Similarity:	210/312 - (67%)	Gaps:	2/312 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 TVKDAAPFDASQDAQVLRAAMKGFGTDEQEIIDVLVGRSNQQRQTIKAVYEAEFERDLVDDLKDE 72
            |:|.|..|||..||:.||.||||||||||.|:||:..|||.|||.|||.::..:.:||:.|||.|
Frog   226 TIKAAPNFDALSDAEKLRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTAYGKDLIKDLKSE 290

  Fly    73 LGGKFEDVIVGLMMPPVEYLCKQLHAAMAGIGTEEATLVEILCTKTNEEMAQIVAVYEERYQRPL 137
            |.|..|::|:.|.||...|....|:.||.|.||:|..|:|||||:||.|:..||:.|:..:.|.:
Frog   291 LSGNVEELIIALFMPATYYDAWSLYHAMKGAGTQERVLIEILCTRTNSEIKNIVSCYKHEFGRDI 355

  Fly   138 AEQMCSETSGFFRRLLTLIVTGVRDGLDTPVDVGQAKEQAAQLYSAGEAKLGTDEEVFNRIMSHA 202
            .:.:.|:|||.|.|||..:..|.||. :..|::.||::.|.:||.|||.||||||..||.:::..
Frog   356 EKDIRSDTSGHFERLLISMCQGNRDE-NQNVNLQQAEQDAQRLYQAGEGKLGTDESSFNLVLASR 419

  Fly   203 SFPQLRLVFEEYKVLSGQTIEQAIKHEMSDELHEAMMAIVECVQSPAAFFANRLYKAMNGAGTDD 267
            ||||||.|.|.|..:|.:.:...|..|.|..:.:.:.|:::|..:..||||.|||::|.||||||
Frog   420 SFPQLRAVAEAYARISKRDLISVIGREFSGYIEDGLKAVLQCAINRPAFFAERLYRSMKGAGTDD 484

  Fly   268 ATLIRIIVSRSEIDLETIKQEFERIYNRTLHSAVVDAETSGDYKRALTALLG 319
            :|||||||:||||||..|||.:.:::.::| ||.:.::|||||:|.|.|:.|
Frog   485 STLIRIIVTRSEIDLVQIKQAYVQMHQKSL-SAAISSDTSGDYRRLLIAIAG 535

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AnxB10	NP_001162804.1	Annexin	19..84	CDD:278615	36/64 (56%)
		Annexin	91..156	CDD:278615	29/64 (45%)
		Annexin	176..241	CDD:278615	27/64 (42%)
		Annexin	251..317	CDD:278615	39/65 (60%)
anxa7	XP_012821793.2	PTZ00009	<158..195	CDD:240227
		Annexin	238..302	CDD:395139	36/63 (57%)
		Annexin	309..374	CDD:395139	29/64 (45%)
		Annexin	392..458	CDD:395139	27/65 (42%)
		Annexin	468..533	CDD:395139	39/65 (60%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	66	1.000	Domainoid score	I9762
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54302
OrthoDB	1	1.010	-	-		D500720at33208
OrthoFinder	1	1.000	-	-		FOG0000105
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X76
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.930