DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AnxB10 and anxa11a

DIOPT Version :9

Sequence 1:	NP_001162804.1	Gene:	AnxB10 / 33019	FlyBaseID:	FBgn0000084	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	NP_861430.2	Gene:	anxa11a / 368215	ZFINID:	ZDB-GENE-030707-4	Length:	526	Species:	Danio rerio

Alignment Length:	314	Identity:	141/314 - (44%)
Similarity:	210/314 - (66%)	Gaps:	2/314 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 TVKDAAPFDASQDAQVLRAAMKGFGTDEQEIIDVLVGRSNQQRQTIKAVYEAEFERDLVDDLKDE 72
            :::|....|..:||:|||.||||||||||.||::|..|||:||..:...|:..:.:||:.|||.|
Zfish   214 SIQDFPGADPLRDAEVLRKAMKGFGTDEQAIINLLGSRSNKQRVPLLVSYKTAYGKDLIKDLKSE 278

  Fly    73 LGGKFEDVIVGLMMPPVEYLCKQLHAAMAGIGTEEATLVEILCTKTNEEMAQIVAVYEERYQRPL 137
            |.|.||.:::.::..|.:|...:|..|:.|.||:||.|:|||.:::|.|:.:|..|::...::.|
Zfish   279 LSGNFEKLVLAMLKTPSQYDAYELKEAIKGAGTDEACLIEILASRSNAEIREINQVFKAENKKSL 343

  Fly   138 AEQMCSETSGFFRRLLTLIVTGVRDGLDTPVDVGQAKEQAAQLYSAGEAKLGTDEEVFNRIMSHA 202
            .:.:..:|||.|||||..:..|.||..:. ||:..||..|..||.|||.||||||..||.|:...
Zfish   344 EDAISGDTSGHFRRLLVSLAQGNRDESEN-VDISIAKTDAQALYQAGENKLGTDESKFNAILCAR 407

  Fly   203 SFPQLRLVFEEYKVLSGQTIEQAIKHEMSDELHEAMMAIVECVQSPAAFFANRLYKAMNGAGTDD 267
            |...||.||.||:.:.|:.||::|:.|||.:|...|:|:|:|:::..|:||.||:|||.||||.|
Zfish   408 SKAHLRAVFNEYQHMCGRDIEKSIEREMSGDLESGMLAVVKCIKNTPAYFAERLHKAMKGAGTKD 472

  Fly   268 ATLIRIIVSRSEIDLETIKQEFERIYNRTLHSAVVDAETSGDYKRALTALLGSA 321
            .|||||:|:|||:|:..|:||:.:.|.::|::| :..:||||||:.|..|.|.:
Zfish   473 RTLIRIMVTRSEVDMLDIRQEYAKNYGKSLYTA-ISGDTSGDYKKLLLKLCGGS 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AnxB10	NP_001162804.1	Annexin	19..84	CDD:278615	34/64 (53%)
		Annexin	91..156	CDD:278615	25/64 (39%)
		Annexin	176..241	CDD:278615	31/64 (48%)
		Annexin	251..317	CDD:278615	35/65 (54%)
anxa11a	NP_861430.2	Bindin	8..>89	CDD:251078
		Annexin	225..290	CDD:278615	34/64 (53%)
		Annexin	297..362	CDD:278615	25/64 (39%)
		Annexin	381..446	CDD:278615	31/64 (48%)
		Annexin	456..521	CDD:278615	35/65 (54%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0819
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54302
OrthoDB	1	1.010	-	-		D500720at33208
OrthoFinder	1	1.000	-	-		FOG0000105
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X76
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.830