DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AnxB10 and anxa6

DIOPT Version :9

Sequence 1:	NP_001162804.1	Gene:	AnxB10 / 33019	FlyBaseID:	FBgn0000084	Length:	321	Species:	Drosophila melanogaster
Sequence 2:	NP_001002038.2	Gene:	anxa6 / 353363	ZFINID:	ZDB-GENE-030707-3	Length:	667	Species:	Danio rerio

Alignment Length:	312	Identity:	142/312 - (45%)
Similarity:	212/312 - (67%)	Gaps:	2/312 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 TVKDAAPFDASQDAQVLRAAMKGFGTDEQEIIDVLVGRSNQQRQTIKAVYEAEFERDLVDDLKDE 72
            ||.|...|||..||:.|..||||||:|::.|:|::..||:.|||.|:..|::::.:||:||||.|
Zfish     8 TVVDHPDFDAGSDAEALYNAMKGFGSDKEAILDLITSRSSAQRQEIRTAYKSQYGKDLIDDLKYE 72

  Fly    73 LGGKFEDVIVGLMMPPVEYLCKQLHAAMAGIGTEEATLVEILCTKTNEEMAQIVAVYEERYQRPL 137
            |.||||.:|||||.||..:..|::..|:.|:||:|..|:|||.::|||::..:||.|.:.|.|.|
Zfish    73 LTGKFERLIVGLMRPPAYHDAKEIKDAIKGVGTDEKCLIEILASRTNEQIHALVAAYSDAYGRDL 137

  Fly   138 AEQMCSETSGFFRRLLTLIVTGVRDGLDTPVDVGQAKEQAAQLYSAGEAKLGTDEEVFNRIMSHA 202
            ...:..:|||.|:::|.:::.|.|:. |..|.....:|.|.:||.||||:.||||..|..::.:.
Zfish   138 EADVIGDTSGHFKKMLVVLLQGTREE-DDVVSEDLVEEDAQELYEAGEAQWGTDEAKFIMLLGNR 201

  Fly   203 SFPQLRLVFEEYKVLSGQTIEQAIKHEMSDELHEAMMAIVECVQSPAAFFANRLYKAMNGAGTDD 267
            |...|:|||:||:.::.::||.:||.|:|.:....|:|:|:|::|...|||.||||:|.|.||.|
Zfish   202 SVTHLQLVFDEYQKIAEKSIEDSIKSELSGDFERLMLAVVQCIRSRPMFFAKRLYKSMKGLGTAD 266

  Fly   268 ATLIRIIVSRSEIDLETIKQEFERIYNRTLHSAVVDAETSGDYKRALTALLG 319
            .|||||:|||||||:..|::.|...|.::|::.:.| :|||||||.|..|.|
Zfish   267 NTLIRIMVSRSEIDMLDIRECFRLRYEKSLYNMIQD-DTSGDYKRTLLKLCG 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AnxB10	NP_001162804.1	Annexin	19..84	CDD:278615	33/64 (52%)
		Annexin	91..156	CDD:278615	24/64 (38%)
		Annexin	176..241	CDD:278615	26/64 (41%)
		Annexin	251..317	CDD:278615	37/65 (57%)
anxa6	NP_001002038.2	Annexin	20..84	CDD:278615	33/63 (52%)
		Annexin	91..156	CDD:278615	24/64 (38%)
		Annexin	175..240	CDD:278615	26/64 (41%)
		Annexin	250..315	CDD:278615	37/65 (57%)
		Annexin	363..427	CDD:278615
		Annexin	434..499	CDD:278615
		Annexin	517..582	CDD:278615
		Annexin	592..662	CDD:278615
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H55558
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D500720at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10502
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X76
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	5.020