Protein Alignment AnxB10 and ANXA6

DIOPT Version :10

• Sequence 1: NP_001162804.1
• Gene: AnxB10 / 33019
• FlyBaseID: FBgn0000084
• Length: 321
• Species: Drosophila melanogaster
• Sequence 2: NP_001146.2
• Gene: ANXA6 / 309
• HGNCID: 544
• Length: 673
• Species: Homo sapiens
• Alignment Length: 312
• Identity: 138/312 - (44%)
• Similarity: 210/312 - (67%)
• Gaps: 2/312 - (0%)

  Fly     8 TVKDAAPFDASQDAQVLRAAMKGFGTDEQEIIDVLVGRSNQQRQTIKAVYEAEFERDLVDDLKDE 72
            ::.|...||.:|||:.|..||||||:|::.|:|::..|||:|||.:...|::.:.:||:.|||.|
Human    13 SIHDFPGFDPNQDAEALYTAMKGFGSDKEAILDIITSRSNRQRQEVCQSYKSLYGKDLIADLKYE 77

  Fly    73 LGGKFEDVIVGLMMPPVEYLCKQLHAAMAGIGTEEATLVEILCTKTNEEMAQIVAVYEERYQRPL 137
            |.||||.:|||||.||.....|::..|::||||:|..|:|||.::|||:|.|:||.|::.|:|.|
Human    78 LTGKFERLIVGLMRPPAYCDAKEIKDAISGIGTDEKCLIEILASRTNEQMHQLVAAYKDAYERDL 142

  Fly   138 AEQMCSETSGFFRRLLTLIVTGVRDGLDTPVDVGQAKEQAAQLYSAGEAKLGTDEEVFNRIMSHA 202
            ...:..:|||.|:::|.:::.|.|:. |..|.....::....||.|||.|.||||..|..|:.:.
Human   143 EADIIGDTSGHFQKMLVVLLQGTREE-DDVVSEDLVQQDVQDLYEAGELKWGTDEAQFIYILGNR 206

  Fly   203 SFPQLRLVFEEYKVLSGQTIEQAIKHEMSDELHEAMMAIVECVQSPAAFFANRLYKAMNGAGTDD 267
            |...|||||:||...:|:.||.:|:.|:|.:..:.|:|:|:|::|...:||.||:|||.|.||.|
Human   207 SKQHLRLVFDEYLKTTGKPIEASIRGELSGDFEKLMLAVVKCIRSTPEYFAERLFKAMKGLGTRD 271

  Fly   268 ATLIRIIVSRSEIDLETIKQEFERIYNRTLHSAVVDAETSGDYKRALTALLG 319
            .|||||:|||||:|:..|::.|...|.::|:| ::..:|||:||:.|..|.|
Human   272 NTLIRIMVSRSELDMLDIREIFRTKYEKSLYS-MIKNDTSGEYKKTLLKLSG 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AnxB10	NP_001162804.1	Annexin	19..84	CDD:395139	33/64 (52%)
		Annexin	91..156	CDD:395139	27/64 (42%)
		Annexin	176..241	CDD:395139	27/64 (42%)
		Annexin	251..317	CDD:395139	33/65 (51%)
ANXA6	NP_001146.2	Annexin 1. /evidence=ECO:0000255|PROSITE-ProRule:PRU01245	20..91		37/70 (53%)
		Annexin	24..89	CDD:395139	33/64 (52%)
		Annexin 2. /evidence=ECO:0000255|PROSITE-ProRule:PRU01245	92..163		29/70 (41%)
		Annexin	97..161	CDD:395139	27/63 (43%)
		Annexin 3. /evidence=ECO:0000255|PROSITE-ProRule:PRU01245	175..247		28/71 (39%)
		Annexin	179..245	CDD:395139	27/65 (42%)
		Annexin 4. /evidence=ECO:0000255|PROSITE-ProRule:PRU01245	251..322		35/71 (49%)
		Annexin	255..320	CDD:395139	33/65 (51%)
		Annexin 5. /evidence=ECO:0000255|PROSITE-ProRule:PRU01245	363..434
		Annexin	368..432	CDD:395139
		Annexin 6. /evidence=ECO:0000255|PROSITE-ProRule:PRU01245	435..506
		Annexin	439..504	CDD:395139
		Annexin 7. /evidence=ECO:0000255|PROSITE-ProRule:PRU01245	521..595
		Annexin	527..593	CDD:395139
		Annexin 8. /evidence=ECO:0000255|PROSITE-ProRule:PRU01245	599..670
		Annexin	603..668	CDD:395139