DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9578 and tiprl

DIOPT Version :9

Sequence 1:	NP_608377.1	Gene:	CG9578 / 33018	FlyBaseID:	FBgn0031094	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_001315355.1	Gene:	tiprl / 393636	ZFINID:	ZDB-GENE-040426-1611	Length:	269	Species:	Danio rerio

Alignment Length:	261	Identity:	106/261 - (40%)
Similarity:	161/261 - (61%)	Gaps:	23/261 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 EFIQFHDWAIKYEKSHILKSSCQLGTAKCCPKDSADRCDLCHYQHSLQLPHLPDMVFHKNRLVLQ 80
            || .|..|.|...|:||:||.                 |:.....::|:|.||:|:|..|.|.:.
Zfish    15 EF-SFGPWIISATKTHIMKSK-----------------DIERLAEAMQMPALPEMLFGDNVLRIW 61

  Fly    81 HKDGATLEFCPMDALALVDNGKQPLEVACAQEWRETR-NEQTMEEKFKPFDWTFTSTYQGTM--- 141
            |.||..:||..:|||..|:|.::.::|||||||:::| ..:...|..|.:|||:|:.|:||:
Zfish    62 HSDGFGIEFNAIDALRRVNNLQESVKVACAQEWQDSRAQSEHSTEAVKRYDWTYTTDYRGTLIGE 126

  Fly   142 NEKVRSETTNQTLNKFKLMQRENIIFYHDLTLFEDELHDHGISVMSVRIRVMPSGFFILLRHFLR 206
            ..:::...|.:.::..||..||.|.|:.|:.||||||||||:|::||:||||||.||:|||.|||
Zfish   127 QTQMKVSPTAERIDMEKLKAREQIKFFEDVLLFEDELHDHGVSMISVKIRVMPSSFFLLLRFFLR 191

  Fly   207 VDHVLIRMHDTRFHHEIENDFILKEYIHREAPCTELQNC-VAFWTNPDEMQEFVPVKSKQLHKLF 270
            ||.||||::|||.:||.....:|:|:..||:...:||:. .|.:|:|:|:...:|::..:..||.
Zfish   192 VDGVLIRINDTRLYHEAGKKHMLREFSTRESNMADLQHIPPAVYTDPNEIAPHLPLRLTECEKLE 256

  Fly   271 F 271
            |
Zfish   257 F 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9578	NP_608377.1	TIP41	79..236	CDD:282083	75/160 (47%)
tiprl	NP_001315355.1	TIP41	59..221	CDD:282083	75/161 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580594
Domainoid	1	1.000	161	1.000	Domainoid score	I4001
eggNOG	1	0.900	-	-		E1_KOG3224
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H7140
Inparanoid	1	1.050	191	1.000	Inparanoid score	I3864
OMA	1	1.010	-	-		QHG54984
OrthoDB	1	1.010	-	-		D1377237at2759
OrthoFinder	1	1.000	-	-		FOG0004871
OrthoInspector	1	1.000	-	-		oto40744
orthoMCL	1	0.900	-	-		OOG6_103322
Panther	1	1.100	-	-	LDO	PTHR21021
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1526
SonicParanoid	1	1.000	-	-		X3435
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800