DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9578 and Tiprl

DIOPT Version :9

Sequence 1:	NP_608377.1	Gene:	CG9578 / 33018	FlyBaseID:	FBgn0031094	Length:	272	Species:	Drosophila melanogaster
Sequence 2:	NP_001103137.1	Gene:	Tiprl / 360869	RGDID:	1310442	Length:	271	Species:	Rattus norvegicus

Alignment Length:	257	Identity:	106/257 - (41%)
Similarity:	158/257 - (61%)	Gaps:	22/257 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 FHDWAIKYEKSHILKSSCQLGTAKCCPKDSADRCDLCHYQHSLQLPHLPDMVFHKNRLVLQHKDG 84
            |..|.:...|:||:||:                 |:......|.:|.||:|:|..|.|.:||..|
  Rat    15 FGPWKLTASKTHIMKSA-----------------DVEKLADELHMPSLPEMMFGDNVLRIQHGSG 62

  Fly    85 ATLEFCPMDALALVDNGKQPLEVACAQEWRETRNE-QTMEEKFKPFDWTFTSTYQGTM---NEKV 145
            ..:||...|||..|:|.:..|:||||:||:|:|.| :..:|..||:|||:|:.|:||:   :.|:
  Rat    63 FGIEFNATDALRCVNNYQGMLKVACAEEWQESRTEGEHSKEVIKPYDWTYTTDYKGTLLGESLKL 127

  Fly   146 RSETTNQTLNKFKLMQRENIIFYHDLTLFEDELHDHGISVMSVRIRVMPSGFFILLRHFLRVDHV 210
            :...|...::..||..||.|.|:.::.||||||||||:|.:||:||||||.||:|||.|||:|.|
  Rat   128 KVVPTTDHIDTEKLKAREQIKFFEEVLLFEDELHDHGVSSLSVKIRVMPSSFFLLLRFFLRIDGV 192

  Fly   211 LIRMHDTRFHHEIENDFILKEYIHREAPCTELQNC-VAFWTNPDEMQEFVPVKSKQLHKLFF 271
            ||||:|||.:||.:..::|:||..||:....|.:. .:.:|.|:|:.:::|:|.....||.|
  Rat   193 LIRMNDTRLYHEADKTYMLREYTSRESKIANLMHVPPSLFTEPNEISQYLPIKEAVCEKLVF 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9578	NP_608377.1	TIP41	79..236	CDD:282083	79/160 (49%)
Tiprl	NP_001103137.1	TIP41	50..218	CDD:398031	82/167 (49%)
Tiprl	NP_001103137.1	Interaction with PPP2CA. /evidence=ECO:0000250	173..271		38/82 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340773
Domainoid	1	1.000	170	1.000	Domainoid score	I3680
eggNOG	1	0.900	-	-		E1_KOG3224
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H7140
Inparanoid	1	1.050	199	1.000	Inparanoid score	I3720
OMA	1	1.010	-	-		QHG54984
OrthoDB	1	1.010	-	-		D1377237at2759
OrthoFinder	1	1.000	-	-		FOG0004871
OrthoInspector	1	1.000	-	-		oto97289
orthoMCL	1	0.900	-	-		OOG6_103322
Panther	1	1.100	-	-	LDO	PTHR21021
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3435
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.770