DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9581 and FASTKD1

DIOPT Version :9

Sequence 1:	NP_608376.1	Gene:	CG9581 / 33017	FlyBaseID:	FBgn0031093	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_001308975.1	Gene:	FASTKD1 / 79675	HGNCID:	26150	Length:	847	Species:	Homo sapiens

Alignment Length:	311	Identity:	60/311 - (19%)
Similarity:	101/311 - (32%)	Gaps:	119/311 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   201 LFGVTEAHPLSQLEAVLA-KRAGALKPHIWFDQKS-----------------TDLPSLAENMLRL 247
            :||..|.:     :|:|: |:.|.....:|..||.                 ..|.:||.|..:|
Human    52 MFGFIERN-----KAILSEKQVGCAFDMLWKLQKQKTSLLKNAEYVRDHPQFLTLHNLATNKFKL 111

  Fly   248 ----------------SGNQQRPLLPAYTFLEAMRLLKSRDEMQLMRRTCDIASRSFNEVMAETR 296
                            :|....||:.|.. .||.|.|: |.:::|:        ..|:..:|
Human   112 MNDDTLVNVLYVTQQFAGEAHDPLVEALV-TEAWRRLE-RFDIKLL--------SEFSSCLA--- 163

  Fly   297 PGQSEHHLFAAIDYKCRMRNASYLAYPPVVAAGKNATVIHYVANSQLLGQQDL----VLMDAGCE 357
                :.||:                :.|::  ||.|.::|    ..|...|||    |||
Human   164 ----DQHLY----------------FSPLM--GKIADIVH----RNLETTQDLSSLSVLM----- 197

  Fly   358 YGGYTSDITRTWPASGVFTEPQRTLYDMLHQLQEEIIGNVMK----------PGGETLDQLFETT 412
             ...:|.|:|.:...  .......|:|.:...:..:..::.|          |..|..:.:|.:.
Human   198 -VNISSLISRHFQQQ--LVNKTELLFDTIDSSEVNVAKSIAKFLRNVRYRYQPLLERCNNVFLSN 259

  Fly   413 CYKLGKYLQEIGLVGKSFSEYKELVSQGYRF--------------CPHHVS 449
            ...|     ::..:.|..|.||.|....:.|              |.|..|
Human   260 VDHL-----DLDSISKILSVYKFLQFNSFEFIIMAKKKLTEMIPLCNHPAS 305

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9581	NP_608376.1	AMP_N	94..232	CDD:282980	8/31 (26%)
CG9581	NP_608376.1	Prolidase	274..517	CDD:238520	36/204 (18%)
FASTKD1	NP_001308975.1	FAST_1	575..642	CDD:284217
		FAST_2	662..742	CDD:285557
		RAP	779..838	CDD:214932
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D352329at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.010