Protein Alignment CG9581 and XPNPEP2

DIOPT Version :9

• Sequence 1: NP_608376.1
• Gene: CG9581 / 33017
• FlyBaseID: FBgn0031093
• Length: 545
• Species: Drosophila melanogaster
• Sequence 2: NP_003390.4
• Gene: XPNPEP2 / 7512
• HGNCID: 12823
• Length: 674
• Species: Homo sapiens
• Alignment Length: 539
• Identity: 112/539 - (20%)
• Similarity: 194/539 - (35%)
• Gaps: 165/539 - (30%)

  Fly    16 RRSAAISTSLWPHRWMSQSTTISPGSP------SSKSTVNAAEVRGV-AQILRQQKGNLGQPTSV 73
            |:..:|:|:|....|.|:...: |..|      :...:....:|.|| :|:.:.||
Human   178 RQLVSITTNLVDLVWGSERPPV-PNQPIYALQEAFTGSTWQEKVSGVRSQMQKHQK--------- 232

  Fly    74 SHPHLIQPDELVPGVELTEIKERRSQLMQNIRAYARSFGGEFNGHS----SSCHMLVLGAASKKY 134
                       ||...|....|..:.|. |:||....:...|..::    ||..:.   |...::
Human   233 -----------VPTAVLLSALEETAWLF-NLRASDIPYNPFFYSYTLLTDSSIRLF---ANKSRF 282

  Fly   135 MSGKIPYVFRQNSDFYYLTGCLEPDAVLLLTIDEAQNVQSELFMRPKDP-------HAELWDGPR 192
            .|..:.|:   ||      .|..|           ..||.|.:.:.:|.       ...:|.|
Human   283 SSETLSYL---NS------SCTGP-----------MCVQIEDYSQVRDSIQAYSLGDVRIWIG-- 325

  Fly   193 TGPELAVPLFGVTEAHPLSQLEAVLAKRAGALKPHIWFDQKSTDLPSLAENMLRLSGNQQRPLLP 257
                .:..::|:.|..|..:|                    .||..|.......:..::::.||.
Human   326 ----TSYTMYGIYEMIPKEKL--------------------VTDTYSPVMMTKAVKNSKEQALLK 366

  Fly   258 AYTFLEAMRLLKSRD--EMQLMRRTCDIASRSFNEVMAETRPGQSEHHLFAAIDYKCRMRNASYL 320
            |....:|:.:::...  |..:.:.|.|..|.:  |::.:.| |:.:.              :|..
Human   367 ASHVRDAVAVIRYLVWLEKNVPKGTVDEFSGA--EIVDKFR-GEEQF--------------SSGP 414

  Fly   321 AYPPVVAAGKNATVIHYVANSQL---LGQQDLVLMDAGCEYGGYTSDITRT--WPASGVFTEPQR 380
            ::..:.|:|.||.:.||....:|   |...::.|:|:|.:|...|:|||||  |.....|   |:
Human   415 SFETISASGLNAALAHYSPTKELNRKLSSDEMYLLDSGGQYWDGTTDITRTVHWGTPSAF---QK 476

  Fly   381 TLYDMLHQLQEEIIGNVMKPGGETLDQLFETTCYKLGKYLQEIGLVGKSFSEY--KELVSQGYRF 443
            ..|..:      :|||:                 .|.:.:......|:....:  :.|...|..:
Human   477 EAYTRV------LIGNI-----------------DLSRLIFPAATSGRMVEAFARRALWDAGLNY 518

  Fly   444 CPHHVSHYLG--MDVHDTP--HVPRNTRIVPGMVFTVEPGIYIGQDCGDVPPEFRGIGIRIEDDL 504
             .|...|.:|  :.||:.|  ....|..:..||..::|||.|  :|     .||   |||:||
Human   519 -GHGTGHGIGNFLCVHEWPVGFQSNNIAMAKGMFTSIEPGYY--KD-----GEF---GIRLED-- 570

  Fly   505 LINENGHVEVLTEACVKDP 523
                   |.::.||..|.|
Human   571 -------VALVVEAKTKYP 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9581	NP_608376.1	AMP_N	94..232	CDD:282980	25/148 (17%)
		Prolidase	274..517	CDD:238520	58/253 (23%)
XPNPEP2	NP_003390.4	Creatinase_N	54..184	CDD:279639	1/5 (20%)
		Creatinase_N_2	202..361	CDD:292807	38/228 (17%)
		PepP	<348..601	CDD:223085	68/298 (23%)
		APP	365..583	CDD:238518	66/281 (23%)
		Peptidase_M24_C	585..648	CDD:292806

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0006
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810