DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9581 and xpnpep3

DIOPT Version :9

Sequence 1:	NP_608376.1	Gene:	CG9581 / 33017	FlyBaseID:	FBgn0031093	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_001016515.1	Gene:	xpnpep3 / 549269	XenbaseID:	XB-GENE-5770341	Length:	502	Species:	Xenopus tropicalis

Alignment Length:	484	Identity:	188/484 - (38%)
Similarity:	285/484 - (58%)	Gaps:	28/484 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 QILRQQKGNLGQPTSVSHPHLIQPDELVPGVELTEIKERRSQLMQNIRAYARSFGGEFNGHSSSC 122
            |:|...|..||||:..:||..::|.|:.||:..||...||.:||..|:..::..|      .|:.
Frog    30 QLLNFPKRYLGQPSPFTHPQCLKPGEVTPGLTQTEYALRRYKLMSLIQTESQVLG------CSTD 88

  Fly   123 HMLVLGAASKKYMSGKIPYVFRQNSDFYYLTGCLEPDAVLLLTIDEAQNVQS---ELFMRPKDPH 184
            |.:::.:....||:..||:.|.||:||.||.|.||||::|||.....|.:.|   :|::..:||.
Frog    89 HAVIILSNPTLYMTSDIPFPFHQNNDFLYLCGFLEPDSILLLQSQSGQALPSHTAKLYVPRRDPG 153

  Fly   185 AELWDGPRTGPELAVPLFGVTEAHPLSQLEAVLAK--RAGALKPHIWFDQKSTDLPSLAENMLR- 246
            .|||||||:|.:.|:.|.||.||....:.:.||.|  ..|..   :|:|......|:|..:.|:
Frog   154 RELWDGPRSGTDGALSLTGVDEAFTTEEFKHVLPKLYDEGVT---VWYDSTIPVHPALHTSSLQP 215

  Fly   247 ------LSGNQQRPLLPAYTFLEAMRLLKSRDEMQLMRRTCDIASRSFNEVMAETRPGQSEHHLF 305
                  .|.|:.|||   ...::.:||:||:.|::||::...|:|::|.|.|:..:....|..|:
Frog   216 LVEFRSRSKNRIRPL---RHLVQQLRLVKSQAELELMKKAGHISSQAFIETMSCRKAPVEEAFLY 277

  Fly   306 AAIDYKCRMRNASYLAYPPVVAAGKNATVIHYVANSQLLGQQDLVLMDAGCEYGGYTSDITRTWP 370
            |..|::||.|.|..||||||||.|..|..:|||.|:|::...::||:|.|||...|.||||||||
Frog   278 AKFDFECRARGADILAYPPVVAGGNRANTLHYVKNNQIIKSGEMVLLDGGCEASCYVSDITRTWP 342

  Fly   371 ASGVFTEPQRTLYDMLHQLQEEIIGNVMKPGGETLDQLFETTCYKLGKYLQEIGLVGKSFSEYKE 435
            .:|.||.||..||..:..:|:..: .:..| |.:|:.::......:.:.|:::.:|.:..|| .:
Frog   343 VNGRFTAPQEALYQAVLDVQKSCL-RLCFP-GTSLENIYSHMLAMIARKLKDLKIVSRGCSE-SQ 404

  Fly   436 LVSQGYRFCPHHVSHYLGMDVHDTPHVPRNTRIVPGMVFTVEPGIYIGQDCGDVPPEFRGIGIRI 500
            |.....::|||||.|||||||||||.|.|:..:.||||.||||||||.:|..:.|.::||:||||
Frog   405 LFKAARKYCPHHVGHYLGMDVHDTPGVSRSVPLQPGMVITVEPGIYIPEDDTEAPQQYRGLGIRI 469

  Fly   501 EDDLLINENGHVEVLTEACVKDPRALQEL 529
            |||::|.|...: :|:..|.|:...:|::
Frog   470 EDDVVITEQSPL-ILSADCPKEIYEMQKV 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9581	NP_608376.1	AMP_N	94..232	CDD:282980	51/142 (36%)
CG9581	NP_608376.1	Prolidase	274..517	CDD:238520	105/242 (43%)
xpnpep3	NP_001016515.1	PRK10879	60..490	CDD:182804	173/445 (39%)
		AMP_N	60..199	CDD:198079	53/147 (36%)
		Prolidase	246..485	CDD:238520	105/242 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	212	1.000	Domainoid score	I2725
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5827
Inparanoid	1	1.050	330	1.000	Inparanoid score	I2403
OMA	1	1.010	-	-		QHG55416
OrthoDB	1	1.010	-	-		D200485at33208
OrthoFinder	1	1.000	-	-		FOG0003565
OrthoInspector	1	1.000	-	-		oto102595
Panther	1	1.100	-	-	LDO	PTHR43226
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2916
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.080