DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9581 and Xpnpep1

DIOPT Version :9

Sequence 1:	NP_608376.1	Gene:	CG9581 / 33017	FlyBaseID:	FBgn0031093	Length:	545	Species:	Drosophila melanogaster
Sequence 2:	NP_573479.3	Gene:	Xpnpep1 / 170750	MGIID:	2180003	Length:	666	Species:	Mus musculus

Alignment Length:	334	Identity:	81/334 - (24%)
Similarity:	129/334 - (38%)	Gaps:	100/334 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   210 LSQLEAVLAKRAGALKPH--IWFDQKSTDLPSLAENMLRLSGNQQRPLLPAYTFLEAMRLLKSRD 272
            ||:|:|:.|.    |.|.  :|...|::...|.|      .....|..:| ||.:...:.:|:..
Mouse   315 LSELKALCAD----LSPREKVWVSDKASYAVSEA------IPKDHRCCMP-YTPICIAKAVKNSA 368

  Fly   273 EMQLMRRT--------CDIASRSFNEVMAET-RPGQSEHHLFAAID--YKCRMRNASY--LAYPP 324
            |...|||.        |::    ||.:..|. :.|.:|   .:|.|  .:.|.:.|.:  |::|.
Mouse   369 ESDGMRRAHIKDAVALCEL----FNWLEQEVPKGGVTE---ISAADKAEEFRRQQADFVDLSFPT 426

  Fly   325 VVAAGKNATVIHYV---ANSQLLGQQDLVLMDAGCEYGGYTSDITRTWPASGVFTEPQRTLYDML 386
            :.:.|.|..:|||.   ..::.|...::.|:|:|.:|...|:|:|||..    |..|  |.|
Mouse   427 ISSTGPNGAIIHYAPVPETNRTLSLDEVYLIDSGAQYKDGTTDVTRTMH----FGTP--TAY--- 482

  Fly   387 HQLQEEIIGNVMK-------------PGGETLDQLFETTCYKLG-KYLQEIGLVGKSFSEYKELV 437
               ::|....|:|             ..|..||....:..:..| .||...|
Mouse   483 ---EKECFTYVLKGHIAVSAAVFPTGTKGHLLDSFARSALWDSGLDYLHGTG------------- 531

  Fly   438 SQGYRFCPHHVSHYLGMDVHDTP-----HVPRNTRIVPGMVFTVEPGIYIGQDCGDVPPEFRGIG 497
                    |.|..:|  :||:.|     ....:..:..||:.|.|||.|          |....|
Mouse   532 --------HGVGSFL--NVHEGPCGISYKTFSDEPLEAGMIVTDEPGYY----------EDGAFG 576

  Fly   498 IRIEDDLLI 506
            ||||:.:|:
Mouse   577 IRIENVVLV 585

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9581	NP_608376.1	AMP_N	94..232	CDD:282980	8/23 (35%)
CG9581	NP_608376.1	Prolidase	274..517	CDD:238520	64/268 (24%)
Xpnpep1	NP_573479.3	Creatinase_N	53..197	CDD:390097
		Creatinase_N_2	200..369	CDD:379790	16/64 (25%)
		APP	372..594	CDD:238518	64/266 (24%)
		Peptidase_M24_C	600..661	CDD:379789
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0006
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810