DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9577 and F58A6.1

DIOPT Version :9

Sequence 1:	NP_608375.1	Gene:	CG9577 / 33016	FlyBaseID:	FBgn0031092	Length:	312	Species:	Drosophila melanogaster
Sequence 2:	NP_494954.1	Gene:	F58A6.1 / 186486	WormBaseID:	WBGene00019022	Length:	278	Species:	Caenorhabditis elegans

Alignment Length:	281	Identity:	121/281 - (43%)
Similarity:	179/281 - (63%)	Gaps:	6/281 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 SGPTGSFKTLAVSSPKPFVFHVELHRPSKFNAISKQMWLEIKECFDGLATNPDCRAIVLSASGKH 98
            |....|.|.:.|.:...||:.|.|:|||||||::..:|.||.:||..:..:|:||.::|...|||
Worm     2 SSKYNSLKLVKVKNVGDFVYKVSLNRPSKFNALNMVIWKEIGDCFQLIDEDPECRVVILQGEGKH 66

  Fly    99 FTAGIDLNDM--INVGQTLAETDDYARKGVSMERMIKVYQDSISSLEHCPKPVITAVHKACIGAG 161
            |.:|:||:::  :| |:   |.||.||:|.|:.|.||..|...:.::.|.||||.|:|..|:||.
Worm    67 FCSGLDLSEVTFLN-GE---EADDSARRGRSILRTIKFMQKQFTYIDECSKPVILAMHGYCLGAA 127

  Fly   162 VDLITAADIRYCTEDAFFQVKEVDIGMAADVGTLQRLPKAVGSQSLARELCFTGRKFEAAEAHSS 226
            :|:.||.|:|..|:||...|||||||||||||||.||||.||:.|..:::..:.|.|.|.||...
Worm   128 LDIATACDVRVATKDAVLSVKEVDIGMAADVGTLNRLPKIVGNHSWIKDISLSARHFSAGEALQF 192

  Fly   227 GLVSRLFPDKDSLLTGALAVAELIASKSPVAVKTTKESLVYSLEHTNQEGLDHILLLNKLNLLSE 291
            ||:||::..::.::...|.:|:|||.||||.|:.||.:|.|:.:||.:..|:::...|...|.::
Worm   193 GLLSRVYDTREEMINEVLKMAKLIALKSPVGVQGTKNALNYARDHTVENSLNYVATWNMSQLFTD 257

  Fly   292 DFAQAVAAQLTKDDKPVFAKL 312
            |..:|..|.|:|...|.|:||
Worm   258 DIMKASMASLSKQPTPPFSKL 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9577	NP_608375.1	crotonase-like	52..310	CDD:304874	113/259 (44%)
CG9577	NP_608375.1	PRK05617	54..309	CDD:235533	112/256 (44%)
F58A6.1	NP_494954.1	crotonase-like	1..275	CDD:304874	118/276 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158880
Domainoid	1	1.000	217	1.000	Domainoid score	I1541
eggNOG	1	0.900	-	-		E1_KOG1681
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1069
Inparanoid	1	1.050	235	1.000	Inparanoid score	I2146
Isobase	1	0.950	-	0.815465	Normalized mean entropy	S2322
OMA	1	1.010	-	-		QHG55028
OrthoDB	1	1.010	-	-		D1094098at2759
OrthoFinder	1	1.000	-	-		FOG0005814
OrthoInspector	1	1.000	-	-		otm14412
orthoMCL	1	0.900	-	-		OOG6_102762
Panther	1	1.100	-	-	LDO	PTHR43149
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3831
SonicParanoid	1	1.000	-	-		X4206
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	17	16.750