DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9577 and Y25C1A.13

DIOPT Version :9

Sequence 1:	NP_608375.1	Gene:	CG9577 / 33016	FlyBaseID:	FBgn0031092	Length:	312	Species:	Drosophila melanogaster
Sequence 2:	NP_494448.1	Gene:	Y25C1A.13 / 173657	WormBaseID:	WBGene00021296	Length:	297	Species:	Caenorhabditis elegans

Alignment Length:	274	Identity:	117/274 - (42%)
Similarity:	175/274 - (63%)	Gaps:	6/274 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 SGPTGSFKTLAVSSPKPFVFHVELHRPSKFNAISKQMWLEIKECFDGLATNPDCRAIVLSASGKH 98
            :.|......::|...:|:|::|:|:||:|.|..:..||.|.|:..|.||.:|.||:|::|..||.
Worm    18 TSPALKSSEISVKEERPYVYNVKLNRPAKLNTFTMDMWREFKKAIDSLADDPKCRSIIISGEGKA 82

  Fly    99 FTAGID----LNDMINVGQTLAETDDYARKGVSMERMIKVYQDSISSLEHCPKPVITAVHKACIG 159
            |.||||    |:|::.:.|.  :|.:..|||..:.:.|...||..::||.||||:|.::|..|:|
Worm    83 FCAGIDIAHGLSDILRIIQD--DTIEVGRKGRLVRKFIGEIQDCYTALERCPKPIIASIHSHCLG 145

  Fly   160 AGVDLITAADIRYCTEDAFFQVKEVDIGMAADVGTLQRLPKAVGSQSLARELCFTGRKFEAAEAH 224
            ||:|||||.|||..::||.|.::|||:|:|||:|||.|:.|.||:.|..|::.||.|.|.|.||.
Worm   146 AGIDLITACDIRVASQDAIFSIREVDVGLAADIGTLNRIQKVVGNDSWTRDVAFTARDFGADEAL 210

  Fly   225 SSGLVSRLFPDKDSLLTGALAVAELIASKSPVAVKTTKESLVYSLEHTNQEGLDHILLLNKLNLL 289
            ..||:||::.|:.|||..::.:|..||.|||:||:.|||:|.|:.||:..:.|:.|...|...||
Worm   211 RFGLISRIYDDRQSLLENSIDMAARIAEKSPIAVQGTKETLNYAREHSTDDSLNFIKTWNMSQLL 275

  Fly   290 SEDFAQAVAAQLTK 303
            |.|...:..|.:.|
Worm   276 STDLLSSAMAVMNK 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9577	NP_608375.1	crotonase-like	52..310	CDD:304874	114/256 (45%)
CG9577	NP_608375.1	PRK05617	54..309	CDD:235533	113/254 (44%)
Y25C1A.13	NP_494448.1	crotonase-like	35..296	CDD:304874	114/257 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	217	1.000	Domainoid score	I1541
eggNOG	1	0.900	-	-		E1_KOG1681
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1069
Inparanoid	1	1.050	235	1.000	Inparanoid score	I2146
Isobase	1	0.950	-	0.815465	Normalized mean entropy	S2322
OMA	1	1.010	-	-		QHG55028
OrthoDB	1	1.010	-	-		D1094098at2759
OrthoFinder	1	1.000	-	-		FOG0005814
OrthoInspector	1	1.000	-	-		otm14412
orthoMCL	1	0.900	-	-		OOG6_102762
Panther	1	1.100	-	-	O	PTHR43149
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3831
SonicParanoid	1	1.000	-	-		X4206
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.820