Protein Alignment Phf7 and G2E3

DIOPT Version :9

• Sequence 1: NP_001259740.1
• Gene: Phf7 / 33015
• FlyBaseID: FBgn0031091
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_060239.2
• Gene: G2E3 / 55632
• HGNCID: 20338
• Length: 706
• Species: Homo sapiens
• Alignment Length: 457
• Identity: 121/457 - (26%)
• Similarity: 203/457 - (44%)
• Gaps: 81/457 - (17%)

  Fly     5 CVLCLS--------GERDELIFGTVHVEGNMMVHRNCLYLSSNLIQRGEKKLSIMNFLKEDIEAE 61
            ||.|..        ||:      ....:.|:.||..||.:||.:.|||:::..:..||.|||..|
Human    14 CVFCRKHDDCPNKYGEK------KTKEKWNLTVHYYCLLMSSGIWQRGKEEEGVYGFLIEDIRKE 72

  Fly    62 VNRCRLLKCCYCRRLGANIWCCKSGCRRTFHTKCGVDNLAQNQFCDTYNSFCHQHVLVPRNRPV- 125
            |||...||||.|::.||:|.|....|:|::|..||:......||...:.|||..|      |||
Human    73 VNRASKLKCCVCKKNGASIGCVAPRCKRSYHFPCGLQRECIFQFTGNFASFCWDH------RPVQ 131

  Fly   126 ------FKNDEECLLCAEDVVAKGERFSVVTCLYAPCCRNGWFHRRCLQRYANSSG-YFFKCPLC 183
                  ::....|.:|.|.:    |.......|.:|||:|.||||.|||..|.::| :||:|.:|
Human   132 IITSNNYRESLPCTICLEFI----EPIPSYNILRSPCCKNAWFHRDCLQVQAINAGVFFFRCTIC 192

  Fly   184 NNTDVFRR-VAYMGIAVLDQDASWETEPDAFAGQYRRDVNCTAALCVAVSGR----ADTSAMLLY 243
            ||:|:|:: :..|||.:.::|||||.|.:|:....:....|....|....||    .|:...:..
Human   193 NNSDIFQKEMLRMGIHIPEKDASWELEENAYQELLQHYERCDVRRCRCKEGRDYNAPDSKWEIKR 257

  Fly   244 CTSCGANPSHYLC-TLKTL-QNYVCKVCSAV----------SPEAVPVAESDSDDAGSMD----- 291
            |..||::.:|..| :|::. ||:.|..|..:          ....:|    :|::.|..|
Human   258 CQCCGSSGTHLACSSLRSWEQNWECLECRGIIYNSGEFQKAKKHVLP----NSNNVGITDCLLEE 318

  Fly   292 DSAEAPR--PGHLNGDQIQEKLSPSHWDDFGSSDDDAVFQRAFDTKVQSRVVTLS---------- 344
            .|.:.||  ||..:.|.:::      ...|..:....:.:..|..|.:::.:.::
Human   319 SSPKLPRQSPGSQSKDLLRQ------GSKFRRNVSTLLIELGFQIKKKTKRLYINKANIWNSALD 377

  Fly   345 -----DDQPSTSAGARALADRGTRTFESQGTQTTFLSSVVTSFRSATATATSSTSTSTSTSASTL 404
                 :..||.:.....:.:......|..|::..|||.::....:::....|.:...:..|.:..
Human   378 AFRNRNFNPSYAIEVAYVIENDNFGSEHPGSKQEFLSLLMQHLENSSLFEGSLSKNLSLNSQALK 442

  Fly   405 DN 406
            :|
Human   443 EN 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phf7	NP_001259740.1	ePHD_PHF7_G2E3_like	5..116	CDD:277139	43/118 (36%)
G2E3	NP_060239.2	ePHD_PHF7_G2E3_like	14..127	CDD:277139	43/118 (36%)
		PHD_PHF7_G2E3_like	232..285	CDD:276971	14/52 (27%)
		HECTc	411..692	CDD:331829	6/34 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110264at33208
OrthoFinder	1	1.000	-	-		FOG0003998
OrthoInspector	1	1.000	-	-		otm41812
orthoMCL	1	0.900	-	-		OOG6_106451
Panther	1	1.100	-	-	LDO	PTHR12420
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10820
SonicParanoid	1	1.000	-	-		X3283
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.850