Protein Alignment Phf7 and pie

DIOPT Version :10

• Sequence 1: NP_608374.1
• Gene: Phf7 / 33015
• FlyBaseID: FBgn0031091
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: NP_524740.2
• Gene: pie / 44315
• FlyBaseID: FBgn0005683
• Length: 582
• Species: Drosophila melanogaster
• Alignment Length: 530
• Identity: 138/530 - (26%)
• Similarity: 216/530 - (40%)
• Gaps: 129/530 - (24%)

  Fly     5 CVLCLSGERDELIFGTVHVEGNMMVHRNCLYLSSNLIQRGEKKLSIMNFLKEDIEAEVNRCRLLK 69
            |::|...:.|:|:||...:..|:.||..||.||::|.|||.....|:.||..||..|.......|
  Fly     9 CLICKYSDTDDLVFGEWMIVRNLQVHYFCLLLSTHLPQRGGDSSGILGFLLRDIREEAAAAEKRK 73

  Fly    70 CCYCRRLGANIWCCKSGCRRTFHTKCGVDNLAQNQFCDTYNSFCHQHVLVPRNRPV--FK----- 127
            |.||.::||::.|.:  ||..||.|||::|.|..:||..|.|:|:      :.||:  :|
  Fly    74 CWYCNKIGASLQCDR--CRSLFHLKCGLENRAVFEFCGQYKSYCY------KCRPMDDYKRQLQS 130

  Fly   128 ---NDEECLLCAEDVVAKGERFSVVTCLYAPCCRNGWFHRRCLQRYANSSGYFFKCPLCNNTDVF 189
               .:..|.:|...:. |.|...||   |..|||.|:.|::|:::||.:|||:.:|..|.:....
  Fly   131 NPPRNATCPICFSSIY-KVELHCVV---YGDCCRLGFAHKKCMRQYALTSGYYLRCIWCRSERFR 191

  Fly   190 RRVAYMGIAVLDQDASWETEPDAFAGQYRRDVNCTAALCVAVSGRA--DTSAMLLYCTSCGANPS 252
            ..:....:.|.|:||:||.:.:|:...:.|::.|....|:..|||.  ..|.::|.|:||.|..:
  Fly   192 DSIRLQSVFVPDRDATWEKQRNAYRELHERNLKCDQPNCLCPSGRTYNRLSWVILCCSSCAATSA 256

  Fly   253 HYLCTLKTLQ--------NYVCKVCSAVSPEAVPVAESDSDDAGSMDDSAEAPRPGHLNGDQIQE 309
            |..|.:..|:        ::.|.:|..|...   :||..:    ...:...|.....::|....:
  Fly   257 HLKCLVGALRLPKKRERTDFKCSMCLDVERR---IAEGPA----RTTEETNADGDNQVDGSFYVQ 314

  Fly   310 KLSPSHWDDFGSSDDDAVFQRAFDTKVQSRVVTLSDDQPSTSAGARALADRGTRTFESQGTQTTF 374
            ||.|                                             |..||:.    |||..
  Fly   315 KLGP---------------------------------------------DAATRSL----TQTPV 330

  Fly   375 LSSVVTSFRSATATATSSTSTSTSTSASTLDNQENTEPSTSNGRRPWRPRYVSPPR-----HVSD 434
            .|....|.||:..|...|...|.:||...                     .:|||:     .:.|
  Fly   331 FSEEDESERSSNITVIFSQPKSNATSERL---------------------SLSPPQEEMIVEIPD 374

  Fly   435 SDDDSDEYDSDEYES----KRRQLT----PTAAA--PSNGRRLLGSISPE-PSTPA----PRVLR 484
            |.:.|.:...||..|    .||..:    |.||:  |.:.:....|..|: |.|.|    |.:.:
  Fly   375 SPEASPKTSIDENHSPQPIARRDTSDSPQPIAASEIPDSPQPTAASEIPDLPQTTAINVNPELTQ 439

  Fly   485 RRTLANRPSS 494
            :..|...|.|
  Fly   440 QTALNTIPHS 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phf7	NP_608374.1	ePHD_PHF7_G2E3_like	5..116	CDD:277139	44/110 (40%)
		RING_Ubox	129..183	CDD:473075	19/53 (36%)
pie	NP_524740.2	PHD_SF	9..117	CDD:473978	44/115 (38%)
		PHD_SF	224..>260	CDD:473978	12/35 (34%)
		PRK10263	<265..>493	CDD:236669	50/262 (19%)