DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Phf7 and g2e3

DIOPT Version :9

Sequence 1:	NP_001259740.1	Gene:	Phf7 / 33015	FlyBaseID:	FBgn0031091	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001003822.1	Gene:	g2e3 / 368848	ZFINID:	ZDB-GENE-030616-400	Length:	706	Species:	Danio rerio

Alignment Length:	382	Identity:	109/382 - (28%)
Similarity:	174/382 - (45%)	Gaps:	55/382 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 ICVLCLSGERDELIFG-TVHVE-GNMMVHRNCLYLSSNLIQRGEKKLSIMNFLKEDIEAEVNRCR 66
            ||.||...|.::..:| .||:| .|:.||..||.:||.:.||||:...:..||..||:.|:.|..
Zfish    19 ICCLCKRSENNKEKYGEKVHLEQHNLAVHFFCLLMSSGICQRGEEDEDVYGFLVGDIKKEIRRSS 83

  Fly    67 LLKCCYCRRLGANIWCCKSGCRRTFHTKCGVDNLAQNQFCDTYNSFCHQHVLVPRNRPVFKNDEE 131
            .|:|.:|::.||::.|....||:..|..||::.....||...:.|||.:|...............
Zfish    84 RLRCFHCKKAGASVGCSIKSCRQMVHMPCGLEQEFVFQFTGLFPSFCKKHAPTQSCDSSHSLPHS 148

  Fly   132 CLLCAEDVVAKGERFSVVTCLYAPCCRNGWFHRRCLQRYANSSG-YFFKCPLCNNTDVFRR-VAY 194
            |.:|. |.:.....:.|:.|   |.|...||||:|:|.||:|:. :||||.||||.:.|:: :..
Zfish   149 CSICL-DPIEPILSYHVLKC---PACHGSWFHRKCVQNYAHSAAMFFFKCTLCNNKEQFQQEMLR 209

  Fly   195 MGIAVLDQDASWETEPDAFAGQYRRDVNCTAALCVAVSGRADTSAM----LLYCTSCGANPSHYL 255
            |||.:.::|||||.|.:||....:....|.|..|:...||..:|..    ::.|..||:..:|..
Zfish   210 MGIYIPERDASWELEENAFVELLQVYHRCDAVKCLCHKGREHSSQSGYFEIVLCKLCGSRGTHRK 274

  Fly   256 CT-LKTLQ-NYVCKVCSAVSPEAVPVAESDSDDAGSMDDSAEAPRPGHLNGD----QIQEKLSPS 314
            |: ::..: :::|..|...:                 :.....|.|.|:...    |.:::|
Zfish   275 CSNIRVYEADWMCADCKTAA-----------------EGKTSLPLPNHVESPLAIRQERKRL--- 319

  Fly   315 HWDDFGSSDDDAVFQRAFDTKVQSRVVTLSDDQPSTSAGARALADRGTRTFESQGTQ 371
                |.|..|           :.|.:|......|:||  ...|.|...:..:.|.|:
Zfish   320 ----FKSISD-----------IHSSIVAKRQCVPATS--PEVLMDLACQISQQQFTE 359

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Phf7	NP_001259740.1	ePHD_PHF7_G2E3_like	5..116	CDD:277139	41/112 (37%)
g2e3	NP_001003822.1	ePHD_PHF7_G2E3_like	20..133	CDD:277139	41/112 (37%)
		PHD_PHF7_G2E3_like	237..290	CDD:276971	12/52 (23%)
		HECTc	433..695	CDD:294058
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110264at33208
OrthoFinder	1	1.000	-	-		FOG0003998
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_106451
Panther	1	1.100	-	-	LDO	PTHR12420
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R10820
SonicParanoid	1	1.000	-	-		X3283
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.850