DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Phf7 and Tcf20

DIOPT Version :9

Sequence 1:	NP_001259740.1	Gene:	Phf7 / 33015	FlyBaseID:	FBgn0031091	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	NP_001107612.1	Gene:	Tcf20 / 21411	MGIID:	108399	Length:	1987	Species:	Mus musculus

Alignment Length:	126	Identity:	28/126 - (22%)
Similarity:	45/126 - (35%)	Gaps:	38/126 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 GERDELIFGTVHVEGN-MMVHRNC------LYLSSNLIQRGEKKLSIMNFLKEDIEAEVNRCRLL 68
            |...||....:.::.| ..||..|      :||....:...::.|.|              .|.:
Mouse  1862 GPELELQIPELPLDSNEFWVHEGCILWANGIYLVCGRLYGLQEALEI--------------AREM 1912

  Fly    69 KCCYCRRLGANIWCCKSGCRRTFHTKCGVDNLAQNQFCDTYNSFCHQH-----VLVPRNRP 124
            ||.:|:..||.:.|...||...:|..|.:|            :.|..|     |..|:::|
Mouse  1913 KCSHCQEAGATLGCYNKGCSFRYHYPCAID------------ADCLLHEENFSVRCPKHKP 1961

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Phf7	NP_001259740.1	ePHD_PHF7_G2E3_like	5..116	CDD:277139	24/111 (22%)
Tcf20	NP_001107612.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..79
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	96..432
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	446..481
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	502..816
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	844..891
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	949..1065
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1136..1372
		Leucine-zipper	1198..1219
		Nuclear localization signal	1282..1295
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1415..1434
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1446..1636
		Nuclear localization signal	1604..1628
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1685..1710
		ePHD_TCF20	1733..1959	CDD:277169	27/122 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1760..1865		1/2 (50%)
		Nuclear localization signal	1812..1819
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1966..1987
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900