DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Phf7 and Setdb2

DIOPT Version :9

Sequence 1:	NP_001259740.1	Gene:	Phf7 / 33015	FlyBaseID:	FBgn0031091	Length:	520	Species:	Drosophila melanogaster
Sequence 2:	XP_038949803.1	Gene:	Setdb2 / 100361710	RGDID:	2319564	Length:	1008	Species:	Rattus norvegicus

Alignment Length:	234	Identity:	53/234 - (22%)
Similarity:	89/234 - (38%)	Gaps:	57/234 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 CVLCLSGERDELIFGTVHVEGNMMVHRNCLYLSSNLIQ-RGEKKLSI-MNFLKEDIEAEVNRCRL 67
            ||||..|....:|:  .....|:..|.|||..||.|:: ......:| .||....:..::.....
  Rat   700 CVLCPEGHDWSVIY--FSPSANIAAHENCLLYSSGLVECEAHDPFNIAKNFDVSSVLEKIWNGST 762

  Fly    68 LKCCYCRRLGANIWCCKSGCRRTFHTKCGVDNLA--QNQFCDTYNSFCHQH-------------V 117
            .||.:|...||.:.|.::.|.:.:|..|..::.|  |.....||..||.:|             :
  Rat   763 SKCSFCNNEGAIMGCDETSCAKNYHLLCAKEDRAILQVGVKRTYKIFCPEHPPQQEETTERANGL 827

  Fly   118 LVPRNR----------PVFKNDEECLLCAEDVV--AKGERFSVVTCLYAPCCRNGWFHRRCLQRY 170
            .:.:.|          |......:|......|.  |.|:|.:.|.   ||      |.::||:
  Rat   828 SIKKRRGRKKRRSLGPPAQPKTMKCRRSRRHVTGEALGQRDAAVK---AP------FLKKCLE-- 881

  Fly   171 ANSSGYFFKCPLCNNTDVFRRVAYMGIAV----LDQDAS 205
               :|..        |::|.::....|::    :|:.||
  Rat   882 ---AGLL--------TELFEQIQQKMISIHGRFMDETAS 909

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Phf7	NP_001259740.1	ePHD_PHF7_G2E3_like	5..116	CDD:277139	32/114 (28%)
Setdb2	XP_038949803.1	HMT_MBD	152..212	CDD:238689
		SET	210..687	CDD:394802
		SET	365..>425	CDD:395687
		PHD_SF	700..813	CDD:419867	32/114 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335112
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930