Protein Alignment Phf7 and kmt2b

DIOPT Version :9

• Sequence 1: NP_001259740.1
• Gene: Phf7 / 33015
• FlyBaseID: FBgn0031091
• Length: 520
• Species: Drosophila melanogaster
• Sequence 2: XP_002940678.3
• Gene: kmt2b / 100144721
• XenbaseID: XB-GENE-853845
• Length: 2817
• Species: Xenopus tropicalis
• Alignment Length: 605
• Identity: 122/605 - (20%)
• Similarity: 190/605 - (31%)
• Gaps: 199/605 - (32%)

  Fly     5 CVLCLS-GERDELIFG-TVHVEGNMMVHRNCLYLSSNLIQRGEKKLSIMNFLKEDIEAEVNRCRL 67
            |.|||. |:.|....| .:::..|...|.||...|:.:.:..:..|       :::.|.|.|.|.
 Frog  1617 CALCLKYGDDDPKDAGRLLYIGQNEWTHINCAIWSAEVFEENDGSL-------KNVHAAVARGRQ 1674

  Fly    68 LKCCYCRRLGANIWCCKSGCRRTFHTKCGVDNLAQNQFCDTYNSFCHQHVLVPRNRPVFKNDEEC 132
            |:|..|:::||.:.||.|.|...||..|.  ..::..|.|....||.:|..:....||   :|:|
 Frog  1675 LRCDNCQKIGATVGCCLSTCHSNFHFMCA--RASRCCFQDDKKMFCSKHTKLLDGTPV---EEDC 1734

  Fly   133 LLCAEDVVAKGERFSVVTCLYAPCCRNGWFHRRCLQ-------------RYANSSGYF------- 177
            ......|....|..|              |.|:.||             ...:|.|..
 Frog  1735 FDVLRRVYVDFEGIS--------------FRRKFLQGLEPDHIHMMIGSMKIDSLGMLNDLSVTE 1785

  Fly   178 -------FKCP-LCNNTDVFRRVAYMGIAVLDQ-DASWETEPDAFAGQYRR------------DV 221
                   ::|. |..:|...||..:....||:. ..|.||.|:...||.:.            ..
 Frog  1786 GKIYPVGYQCSRLYWSTQDARRQCWYKCRVLEHCPNSGETHPEGGEGQEQNKTIVHSPGPLPDPT 1850

  Fly   222 NCTAALCVAVSGRADTSAMLLYCTSCGANP------------SHYLCTLKTLQNYVCKVCSAVSP 274
            ...||....:.  ||||      :|||..|            |.....:|| .||        ||
 Frog  1851 EMEAAFSPPLP--ADTS------SSCGQPPPLQPNTSATAPRSFIGARMKT-PNY--------SP 1898

  Fly   275 EAVPVAESDSDDAGSMDDSAEAPRPGHLNGDQI------------------QEKLSPSHWDDFGS 321
            ...|:..|          |...|.||......:                  :..:.||.::  ..
 Frog  1899 SRRPLGGS----------SRPLPSPGSPTSSSLSHHILTVSDPEVTPLRRTRRPVPPSRFN--AP 1951

  Fly   322 SDDDAVFQRAFDTKVQSRVV-----TLSDDQP--------------STSAGARALADRGTRTFES 367
            |...:..:....:.:.:|.|     |..::.|              |:|.|...|...|.:....
 Frog  1952 SSTRSPEETTSPSPLPARPVIRHRATSENEVPTPASCGGASEVEVMSSSDGGALLGPCGAQLIVG 2016

  Fly   368 QGTQTTFLSSVVTSFRSATATATSSTS-TSTSTSASTL------------DNQENTE-------- 411
            ....::........:...|.|..|... :|...|||::            |:::.::
 Frog  2017 SEGDSSSEEDADDQYYGLTRTVVSGDKISSMPASASSVHIRQLDGIHDSTDSEDGSQGPCGPIGG 2081

  Fly   412 -------PS---------TSNGRRPWRPRYVSPPRHVSDSDDDSDEYDSDEYESKRRQLTPTAAA 460
                   ||         |.|.....:..::.||..|:.|...|...:.|            |..
 Frog  2082 GKTPSHIPSEIVEFVLKNTGNSESSIQLHHIGPPASVASSSSSSSAQNGD------------ATL 2134

  Fly   461 PSNGRRLLGSISPEPSTPAP 480
            .|||.   |::|.:||...|
 Frog  2135 LSNGN---GAVSRQPSQGPP 2151

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Phf7	NP_001259740.1	ePHD_PHF7_G2E3_like	5..116	CDD:277139	33/112 (29%)
kmt2b	XP_002940678.3	zf-CXXC	1011..1058	CDD:366873
		PHD1_KMT2B	1233..1279	CDD:277064
		PHD2_KMT2A_like	1281..1330	CDD:276982
		PHD3_KMT2B	1367..1423	CDD:277068
		Bromodomain	1406..1548	CDD:413371
		ePHD_KMT2B	1617..1721	CDD:277164	33/112 (29%)
		FYRN	1768..1815	CDD:399155	7/46 (15%)
		PHA03307	1824..>2091	CDD:223039	49/295 (17%)
		PHA03247	<2141..2441	CDD:223021	4/11 (36%)
		FYRC	2512..2595	CDD:399156
		SET_KMT2A_2B	2664..2817	CDD:380947

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910