Protein Alignment Rab35 and RAB9A

DIOPT Version :10

• Sequence 1: NP_608373.1
• Gene: Rab35 / 33014
• FlyBaseID: FBgn0031090
• Length: 201
• Species: Drosophila melanogaster
• Sequence 2: NP_004242.1
• Gene: RAB9A / 9367
• HGNCID: 9792
• Length: 201
• Species: Homo sapiens
• Alignment Length: 211
• Identity: 83/211 - (39%)
• Similarity: 120/211 - (56%)
• Gaps: 26/211 - (12%)

  Fly     4 GFDHLFKLLIIGDSGVGKSSLLIRFSDDTFSGSYITTIGVDFKIRTVDIEGMRVKLQIWDTAGQE 68
            |...|||::::||.|||||||:.|:..:.|......||||:|..:.::::|..|.:|||||||||
Human     3 GKSSLFKVILLGDGGVGKSSLMNRYVTNKFDTQLFHTIGVEFLNKDLEVDGHFVTMQIWDTAGQE 67

  Fly    69 RFRTITSTYYRGTHGVIVVYDVTNGESFANVRRWLEEIQNNCDVVKK-----VLVGNKNDDPDRK 128
            |||::.:.:|||:...::.:.|.:.:||.|:..|.:|.....||.:.     |::|||.|..:|:
Human    68 RFRSLRTPFYRGSDCCLLTFSVDDSQSFQNLSNWKKEFIYYADVKEPESFPFVILGNKIDISERQ 132

  Fly   129 VVITEDAQRFAKQM-DIELFETSAKDNINVENMFLSITRQVL------DHKLRTSPNEQQKDT-- 184
             |.||:||.:.:.. |...|||||||..||...|....|:||      ||.::|       ||
Human   133 -VSTEEAQAWCRDNGDYPYFETSAKDATNVAAAFEEAVRRVLATEDRSDHLIQT-------DTVN 189

  Fly   185 LHLKPNPKGSKGGKCC 200
            ||.||.|..|    ||
Human   190 LHRKPKPSSS----CC 201

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab35	NP_608373.1	Rab35	3..201	CDD:133310	83/211 (39%)
RAB9A	NP_004242.1	Rab9	3..172	CDD:206697	68/169 (40%)
		Switch 1. /evidence=ECO:0000269|PubMed:34793709, ECO:0007744|PDB:7E1T	31..42		3/10 (30%)
		Switch 2. /evidence=ECO:0000269|PubMed:34793709, ECO:0007744|PDB:7E1T	64..78		7/13 (54%)