Protein Alignment Rab35 and RAB2B

DIOPT Version :10

• Sequence 1: NP_608373.1
• Gene: Rab35 / 33014
• FlyBaseID: FBgn0031090
• Length: 201
• Species: Drosophila melanogaster
• Sequence 2: NP_116235.2
• Gene: RAB2B / 84932
• HGNCID: 20246
• Length: 216
• Species: Homo sapiens
• Alignment Length: 215
• Identity: 86/215 - (40%)
• Similarity: 129/215 - (60%)
• Gaps: 20/215 - (9%)

  Fly     5 FDHLFKLLIIGDSGVGKSSLLIRFSDDTFSGSYITTIGVDFKIRTVDIEGMRVKLQIWDTAGQER 69
            :.:|||.:||||:|||||.||::|:|..|...:..||||:|..|.|:|:|.::|||||||||||.
Human     3 YAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIWDTAGQES 67

  Fly    70 FRTITSTYYRGTHGVIVVYDVTNGESFANVRRWLEEI-QNNCDVVKKVLVGNKNDDPDRKVVITE 133
            ||:||.:||||..|.::|||:|..|:|.::..|||:. |::...:..:|:|||:|...|:.|..|
Human    68 FRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNKSDLESRRDVKRE 132

  Fly   134 DAQRFAKQMDIELFETSAKDNINVENMFLSITRQV---LDHKLRTSPNE--------QQKDTLHL 187
            :.:.||::..:...|||||...|||..|::..:::   :...|....||        ||..:..:
Human   133 EGEAFAREHGLIFMETSAKTACNVEEAFINTAKEIYRKIQQGLFDVHNEANGIKIGPQQSISTSV 197

  Fly   188 KPNPK-------GSKGGKCC 200
            .|:..       ||..| ||
Human   198 GPSASQRNSRDIGSNSG-CC 216

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab35	NP_608373.1	Rab35	3..201	CDD:133310	86/215 (40%)
RAB2B	NP_116235.2	PLN03108	1..216	CDD:178655	84/213 (39%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P61106	37..42		3/4 (75%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P61106	63..72		6/8 (75%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	189..216		6/27 (22%)