Protein Alignment Rab35 and RAB6C

DIOPT Version :10

• Sequence 1: NP_608373.1
• Gene: Rab35 / 33014
• FlyBaseID: FBgn0031090
• Length: 201
• Species: Drosophila melanogaster
• Sequence 2: NP_115520.2
• Gene: RAB6C / 84084
• HGNCID: 16525
• Length: 254
• Species: Homo sapiens
• Alignment Length: 196
• Identity: 68/196 - (34%)
• Similarity: 109/196 - (55%)
• Gaps: 5/196 - (2%)

  Fly     9 FKLLIIGDSGVGKSSLLIRFSDDTFSGSYITTIGVDFKIRTVDIEGMRVKLQIWDTAGQERFRTI 73
            |||:.:|:..|.|:||:.||..|:|..:|...||:||..:|:.:|...:.|::||||||||.|::
Human    14 FKLVFLGEQSVAKTSLITRFRYDSFDNTYQAIIGIDFLSKTMYLEDGTIGLRLWDTAGQERLRSL 78

  Fly    74 TSTYYRGTHGVIVVYDVTNGESFANVRRWLEEI--QNNCDVVKKVLVGNKNDDPDRKVVITEDAQ 136
            ...|.|.:...:||||:||..||....:|::::  :...||: ..||||:.|..|::.|..|:.:
Human    79 IPRYIRDSAAAVVVYDITNVNSFQQTTKWIDDVRTERGSDVI-ITLVGNRTDLADKRQVSVEEGE 142

  Fly   137 RFAKQMDIELFETSAKDNINVENMFLSITRQVLD-HKLRTSPNEQQKDTLHLKPNPKG-SKGGKC 199
            |.||.:::...||.||...||:.:|..:...:.. ...:....|...|....||..:. |:||..
Human   143 RKAKGLNVTFIETRAKAGYNVKQLFRRVAAALPGMESTQDGSREDMSDIKLEKPQEQTVSEGGCS 207

  Fly   200 C 200
            |
Human   208 C 208

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab35	NP_608373.1	Rab35	3..201	CDD:133310	68/196 (35%)
RAB6C	NP_115520.2	Required for centrosome localization	1..174		60/160 (38%)
		Rab6	14..174	CDD:206654	60/160 (38%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P20340	32..50		7/17 (41%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P20340	69..88		9/18 (50%)