Protein Alignment Rab35 and Rab32

DIOPT Version :10

• Sequence 1: NP_608373.1
• Gene: Rab35 / 33014
• FlyBaseID: FBgn0031090
• Length: 201
• Species: Drosophila melanogaster
• Sequence 2: NP_080681.1
• Gene: Rab32 / 67844
• MGIID: 1915094
• Length: 223
• Species: Mus musculus
• Alignment Length: 214
• Identity: 74/214 - (34%)
• Similarity: 116/214 - (54%)
• Gaps: 30/214 - (14%)

  Fly     6 DHLFKLLIIGDSGVGKSSLLIRFSDDTFSGSYITTIGVDFKIRTVDIEGMR-VKLQIWDTAGQER 69
            :||||:|:||:.||||:|::.|:....||..|..||||||.::.::.:... |:||:||.|||||
Mouse    21 EHLFKVLVIGELGVGKTSIIKRYVHQLFSQHYRATIGVDFALKVLNWDSRTLVRLQLWDIAGQER 85

  Fly    70 FRTITSTYYRGTHGVIVVYDVTNGESFANVRRWLEEIQN-----NCDVVKKVLVGNKNDDPDRKV 129
            |..:|..||:...|..||:|::...:|..|.:|..::.:     |...:..||:.||.|.
Mouse    86 FGNMTRVYYKEALGAFVVFDISRSSTFDAVLKWKNDLDSKVHLPNGSPIPAVLLANKCDQ----- 145

  Fly   130 VITEDAQRFAKQMD--------IELFETSAKDNINVENMFLSITRQVLDHKL---RTSPNEQ-QK 182
              .:|..:...|||        ...||||||||||::    ..||.::::.|   ::.|:|: ..
Mouse   146 --KKDNSQSPSQMDQFCKDHGFTGWFETSAKDNINID----EATRFLVENMLANQQSFPSEEIDL 204

  Fly   183 DTLHLKPNPKGSK-GGKCC 200
            |.:.|...|..:| ..:||
Mouse   205 DRIKLVEEPPTTKPRSQCC 223

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab35	NP_608373.1	Rab35	3..201	CDD:133310	74/214 (35%)
Rab32	NP_080681.1	Rab32_Rab38	24..222	CDD:206692	70/208 (34%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:Q13637	46..60		7/13 (54%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:Q13637	82..95		7/12 (58%)
		PKA-RII subunit binding domain. /evidence=ECO:0000250	176..195		6/22 (27%)