Protein Alignment Rab35 and Rab5a

DIOPT Version :10

• Sequence 1: NP_608373.1
• Gene: Rab35 / 33014
• FlyBaseID: FBgn0031090
• Length: 201
• Species: Drosophila melanogaster
• Sequence 2: NP_073183.1
• Gene: Rab5a / 64633
• RGDID: 620936
• Length: 215
• Species: Rattus norvegicus
• Alignment Length: 206
• Identity: 73/206 - (35%)
• Similarity: 112/206 - (54%)
• Gaps: 27/206 - (13%)

  Fly     9 FKLLIIGDSGVGKSSLLIRFSDDTFSGSYITTIGVDFKIRTVDIEGMRVKLQIWDTAGQERFRTI 73
            |||:::|:|.||||||::||....|.....:|||..|..:||.::...||.:|||||||||:.::
  Rat    21 FKLVLLGESAVGKSSLVLRFVKGQFHEFQESTIGAAFLTQTVCLDDTTVKFEIWDTAGQERYHSL 85

  Fly    74 TSTYYRGTHGVIVVYDVTNGESFANVRRWLEEIQNNCDV-VKKVLVGNKNDDPDRKVVITEDAQR 137
            ...||||....|||||:||.|||:..:.|::|:|..... :...|.|||.|..:::.|..::||.
  Rat    86 APMYYRGAQAAIVVYDITNEESFSRAKNWVKELQRQASPNIVIALSGNKADLANKRAVDFQEAQS 150

  Fly   138 FAKQMDIELFETSAKDNINVENMFLSITRQVLDHKLRTSPNEQQKDTLHLKPNPKGSKG------ 196
            :|....:...|||||.::||..:|::|.:::       ..||.|      .|....::|
  Rat   151 YADDNSLLFMETSAKTSMNVNEIFMAIAKKL-------PKNEPQ------NPGANSARGRGVDLT 202

  Fly   197 -------GKCC 200
                   .:||
  Rat   203 EPAQPARSQCC 213

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab35	NP_608373.1	Rab35	3..201	CDD:133310	73/206 (35%)
Rab5a	NP_073183.1	Rab5_related	20..182	CDD:206653	66/167 (40%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P20339	44..56		4/11 (36%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P20339	77..93		8/15 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	181..215		7/46 (15%)