Protein Alignment Rab35 and RAB27A

DIOPT Version :10

• Sequence 1: NP_608373.1
• Gene: Rab35 / 33014
• FlyBaseID: FBgn0031090
• Length: 201
• Species: Drosophila melanogaster
• Sequence 2: NP_004571.2
• Gene: RAB27A / 5873
• HGNCID: 9766
• Length: 221
• Species: Homo sapiens
• Alignment Length: 165
• Identity: 69/165 - (41%)
• Similarity: 109/165 - (66%)
• Gaps: 12/165 - (7%)

  Fly     5 FDHLFKLLIIGDSGVGKSSLLIRFSDDTFSGSYITTIGVDFKIRTVDI----------EGMRVKL 59
            :|:|.|.|.:|||||||:|:|.:::|..|:..:|||:|:||:.:.|..          .|.|:.|
Human     6 YDYLIKFLALGDSGVGKTSVLYQYTDGKFNSKFITTVGIDFREKRVVYRASGPDGATGRGQRIHL 70

  Fly    60 QIWDTAGQERFRTITSTYYRGTHGVIVVYDVTNGESFANVRRWLEEIQNN--CDVVKKVLVGNKN 122
            |:||||||||||::|:.::|...|.::::|:||.:||.|||.|:.::|.:  |:....||.|||:
Human    71 QLWDTAGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWISQLQMHAYCENPDIVLCGNKS 135

  Fly   123 DDPDRKVVITEDAQRFAKQMDIELFETSAKDNINV 157
            |..|::||..|:|...|::..|..|||||.:..|:
Human   136 DLEDQRVVKEEEAIALAEKYGIPYFETSAANGTNI 170

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab35	NP_608373.1	Rab35	3..201	CDD:133310	69/165 (42%)
RAB27A	NP_004571.2	Rab27A	6..185	CDD:206700	69/165 (42%)
		Effector region. /evidence=ECO:0000250	38..46		4/7 (57%)