DRSC/TRiP Functional Genomics Resources

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Protein Alignment Rab35 and RAB13

DIOPT Version :9

Sequence 1:NP_001188678.1 Gene:Rab35 / 33014 FlyBaseID:FBgn0031090 Length:201 Species:Drosophila melanogaster
Sequence 2:NP_002861.1 Gene:RAB13 / 5872 HGNCID:9762 Length:203 Species:Homo sapiens


Alignment Length:201 Identity:101/201 - (50%)
Similarity:143/201 - (71%) Gaps:3/201 - (1%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MARGFDHLFKLLIIGDSGVGKSSLLIRFSDDTFSGSYITTIGVDFKIRTVDIEGMRVKLQIWDTA 65
            ||:.:|||||||:||||||||:.|:|||::|.|:.:||:|||:|||||||||||.::|||:||||
Human     1 MAKAYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKIKLQVWDTA 65

  Fly    66 GQERFRTITSTYYRGTHGVIVVYDVTNGESFANVRRWLEEIQNNCDV-VKKVLVGNKNDDPDRKV 129
            |||||:|||:.||||..|:|:|||:|:.:||.|::.|::.|:.|... |:::|:|||.|...::.
Human    66 GQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLGNKCDMEAKRK 130

  Fly   130 VITEDAQRFAKQMDIELFETSAKDNINVENMFLSITRQV-LDHKLRTSPNEQQKDTLHLKPNPKG 193
            |..|.|.:.|::..|..||||||.::||:..|.|:.|.: |....|.|.|..:..:..||...| 
Human   131 VQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDILLKSGGRRSGNGNKPPSTDLKTCDK- 194

  Fly   194 SKGGKC 199
            ....||
Human   195 KNTNKC 200

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rab35NP_001188678.1 Rab35 3..201 CDD:133310 99/199 (50%)
RAB13NP_002861.1 Rab8_Rab10_Rab13_like 6..172 CDD:206659 90/165 (55%)
Effector region. /evidence=ECO:0000250 37..45 5/7 (71%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 173..203 8/29 (28%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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