Protein Alignment Rab35 and RAB13

DIOPT Version :10

• Sequence 1: NP_608373.1
• Gene: Rab35 / 33014
• FlyBaseID: FBgn0031090
• Length: 201
• Species: Drosophila melanogaster
• Sequence 2: NP_002861.1
• Gene: RAB13 / 5872
• HGNCID: 9762
• Length: 203
• Species: Homo sapiens
• Alignment Length: 201
• Identity: 101/201 - (50%)
• Similarity: 143/201 - (71%)
• Gaps: 3/201 - (1%)

  Fly     1 MARGFDHLFKLLIIGDSGVGKSSLLIRFSDDTFSGSYITTIGVDFKIRTVDIEGMRVKLQIWDTA 65
            ||:.:|||||||:||||||||:.|:|||::|.|:.:||:|||:|||||||||||.::|||:||||
Human     1 MAKAYDHLFKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKIKLQVWDTA 65

  Fly    66 GQERFRTITSTYYRGTHGVIVVYDVTNGESFANVRRWLEEIQNNCDV-VKKVLVGNKNDDPDRKV 129
            |||||:|||:.||||..|:|:|||:|:.:||.|::.|::.|:.|... |:::|:|||.|...::.
Human    66 GQERFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLGNKCDMEAKRK 130

  Fly   130 VITEDAQRFAKQMDIELFETSAKDNINVENMFLSITRQV-LDHKLRTSPNEQQKDTLHLKPNPKG 193
            |..|.|.:.|::..|..||||||.::||:..|.|:.|.: |....|.|.|..:..:..||...|
Human   131 VQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDILLKSGGRRSGNGNKPPSTDLKTCDK- 194

  Fly   194 SKGGKC 199
            ....||
Human   195 KNTNKC 200

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab35	NP_608373.1	Rab35	3..201	CDD:133310	99/199 (50%)
RAB13	NP_002861.1	Rab8_Rab10_Rab13_like	6..172	CDD:206659	90/165 (55%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P62820	31..45		7/13 (54%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P62820	63..80		13/16 (81%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	173..203		8/29 (28%)